Dovitinib
CAS: 405169-16-6
Ref. TM-T6289
5mg | 46.00 € | ||
10mg | 69.00 € | ||
25mg | 123.00 € | ||
50mg | 199.00 € | ||
100mg | 321.00 € | ||
200mg | 479.00 € | ||
500mg | 766.00 € | ||
1ml*10 (DMSO) | 50.00 € |
Product Information
- TKI258, CHIR-258
- 2(1H)-Quinolinone, 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
- 2(1H)-Quinolinone, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
- 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
- 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
- Gfki 258
- Tk-258
- Tki 258
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER2.
Chemical properties
Technical inquiry about: TM-T6289 Dovitinib
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