CAS 4091-99-0
:2′,7′-Dichlorodihydrofluorescein diacetate
Description:
2′,7′-Dichlorodihydrofluorescein diacetate (DCFH-DA) is a non-fluorescent, cell-permeable compound widely used as a probe for detecting reactive oxygen species (ROS) in biological systems. Upon entering cells, DCFH-DA is hydrolyzed by intracellular esterases to form dichlorodihydrofluorescein (DCFH), which can then be oxidized by ROS to produce a highly fluorescent compound, dichlorofluorescein (DCF). This transformation allows for the quantification of oxidative stress within cells. DCFH-DA is characterized by its stability, ease of use, and ability to provide real-time measurements of ROS levels. It is typically utilized in various applications, including cell culture studies, flow cytometry, and fluorescence microscopy. The compound is soluble in organic solvents and has a relatively low toxicity profile, making it suitable for in vitro experiments. However, care must be taken to avoid light exposure during experiments, as fluorescence can be affected by photobleaching. Overall, DCFH-DA is a valuable tool in the field of cellular biology and oxidative stress research.
Formula:C24H16Cl2O7
InChI:InChI=1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
InChI key:InChIKey=PXEZTIWVRVSYOK-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(C2C=3C(OC=4C2=CC(Cl)=C(OC(C)=O)C4)=CC(OC(C)=O)=C(Cl)C3)C=CC=C1
Synonyms:- 2,7-Dichlorodihydrofluorescein diacetate (2,7-Dichlorofluorescin diacetate
- 2-(3,6-Diacetoxy-2,7-dichloro-9H-xanthen-9-yl)benzoic acid
- 2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid
- 2′,7′-Dichlorodihydrofluorescein diacetate
- Benzoic acid, 2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]-
- Benzoic acid, o-(2,7-dichloro-3,6-dihydroxyxanthen-9-yl)-, diacetate
- Dcfh-Da
- H2Dcfda
- H<sub>2</sub>DCFDA
- DCFH
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Found 10 products.
2',7'-Dichlorodihydrofluorescein Diacetate
CAS:Formula:C24H16Cl2O7Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:487.29H2DCFDA
CAS:<p>H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525</p>Formula:C24H16Cl2O7Purity:97.04% - 99.47%Color and Shape:SolidMolecular weight:487.29Benzoic acid, 2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]-
CAS:Formula:C24H16Cl2O7Purity:97%Color and Shape:SolidMolecular weight:487.28562',7'-Dichlorodihydrofluorescein Diacetate
CAS:2',7'-Dichlorodihydrofluorescein DiacetatePurity:97%Molecular weight:487.29g/mol2'',7''-Dichlorofluorescin diacetate
CAS:Formula:C24H16Cl2O7Purity:≥ 95.0%Color and Shape:White to off-white powderMolecular weight:487.292,7-Dichlorodihydrofluorescein diacetate
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:487.29000854492192',7'-Dichlorodihydrofluorescein diacetate
CAS:<p>Cell permeable reagent for use in detection of peroxidase activity</p>Formula:C24H16Cl2O7Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:487.29 g/mol2,7-Dichlorofluorescein Diacetate (DCFH) extrapure, 97%
CAS:Formula:C24H16Cl2O7Purity:min. 97%Color and Shape:White to off - white to pale yellow, Crystalline powderMolecular weight:487.292',7'-Dichlorodihydrofluorescein Diacetate
CAS:<p>Stability Light Sensitive<br>Applications 2',7'-Dichlorodihydrofluorescein as a cell-permeable non-fluorescent probe. It is de-esterified intracellularly and turns to highly fluorescent 2′,7′-dichlorofluorescein upon oxidation.<br>References Lebel, C., et al.: Chem. Res. Toxicol., 5, 227 (1992), Kjaer, M., et al.: Lipids, 43, 813 (2008), Baron, C., et al.: J. Agric. Food Chem., 57, 4185 (2009),<br></p>Formula:C24H16Cl2O7Color and Shape:ColourlessMolecular weight:487.29
![Benzoic acid, 2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I80J.jpg&w=3840&q=75)
