CAS 4205-91-8

Clonidine hydrochloride

Description:

Clonidine hydrochloride is a medication primarily used to treat high blood pressure and attention deficit hyperactivity disorder (ADHD). It is an alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to a decrease in sympathetic outflow and a subsequent reduction in heart rate and blood pressure. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets and transdermal patches. Clonidine hydrochloride has a molecular formula of C9H9ClN2HCl and a molecular weight of approximately 230.1 g/mol. Its pharmacological effects can also include sedation and analgesia, which is why it is sometimes used in managing withdrawal symptoms from opioids. However, it can cause side effects such as dry mouth, drowsiness, and hypotension. Due to its mechanism of action, careful monitoring is required when initiating or adjusting doses, especially in patients with cardiovascular conditions.

Formula: C₉H₁₀Cl₃N₃

InChI: InChI=1/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-4,9,13-14H,5H2;1H

InChI key: InChIKey=ZNIFSRGNXRYGHF-UHFFFAOYSA-N

SMILES: N(C1=C(Cl)C=CC=C1Cl)C=2NCCN2.Cl

Synonyms:

• 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, hydrochloride (1:1)
• 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride
• 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
• 2-Imidazoline, 2-(2,6-dichloroanilino)-, monohydrochloride
• 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline hydrochloride
• 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline monohydrochloride
• Atensina
• Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride
• Capresin
• Catapres
• Catapresan
• Catapressan
• Chlophazolin
• Clofelin
• Clonidina, Clorhidrato
• Clonidine Hcl
• Clonidine chloride
• Clonidine monohydrochloride
• Clonidine, Chlorhydrate
• Clonidinhydrochlorid
• Clopheline
• Dcai
• Dichloranilino imidazolin
• Haemiton
• Hemiton
• Isoglaucon
• Kapvay
• Katapresan
• N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride (1:1)
• Neuclon
• Normopresan
• St 155
• 2-((2,6-dichlorophenyl)imino)imidazolidinemonohydrochloride
• clonidinemonohydrochloride
• CLONIDINE HYDROCHLORIDE
• DIXARIT
• TIMTEC-BB SBB003065
• 2-(2,6-dichloroanilino)-2-imidazolinmonohydrochloride
• 2-(2,6-dichlorophenylamino)-2-imidazolinhydrochlorid
• 2-[2,6-DICHLOROANILINE]-2-IMIDAZOLINE HYDROCHLORIDE
• 2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE, HCL
• 2,6-dichloro-n-2-imidazolidinylidene-benzenaminhydrochloride

Clonidine Hydrochloride

CAS: 4205-91-8

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₉H₉Cl₂N₃·ClH

Color and Shape: White Powder

Molecular weight: 264.99403

Ref: 45-1140407

Clonidine Hydrochloride

CAS: 4205-90-7, 4205-91-8

Formula: C₉H₉Cl₂N₃·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 266.55

Ref: 3B-D1353

Clonidine hydrochloride, 98+%

CAS: 4205-91-8

Clonidine hydrochloride tablets are indicated in the treatment of hypertension. It has found new uses, including treatment of some types of neuropathic pain, opioid detoxification, sleep hyperhidrosis, anaesthetic use, and off-label, to counter the side effects of stimulant medications such as methy

Formula: C₉H₁₀Cl₃N₃

Purity: 98+%

Molecular weight: 266.55

Ref: 02-J63707

Clonidine Hydrochloride

CAS: 4205-91-8

Color and Shape: Neat

Ref: 61-FOR0983.00

Clonidine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 4205-91-8

Color and Shape: Single Solution

Ref: 61-AMP0983.00-01

Clonidine hydrochloride

CAS: 4205-91-8

Clonidine hydrochloride

Formula: C₉H₉Cl₂N₃HCl

Purity: 99.8%

Color and Shape: White

Molecular weight: 264.99403

Ref: 47-85

CLONIDINE HYDROCHLORIDE CRS

CAS: 4205-91-8

CLONIDINE HYDROCHLORIDE CRS

Ref: 41-C2400000

Clonidine hydrochloride

CAS: 4205-91-8

Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.

Formula: C₉H₁₀Cl₃N₃

Purity: 99.16% - 99.86%

Color and Shape: Solid

Molecular weight: 266.55

Ref: TM-T1247

Clonidine hydrochloride

CAS: 4205-91-8

Clonidine hydrochloride

Purity: ≥98%

Molecular weight: 266.55g/mol

Ref: 54-BUP14908

Clonidine HCl

CAS: 4205-91-8

Formula: C₉H₉Cl₂N₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 230.09 36.46

Ref: 4Z-C-258

Clonidine hydrochloride, Ph. Eur. grade

CAS: 4205-91-8

Formula: C₉H₉Cl₂N₃·HCl

Purity: ≤ 0.1%

Color and Shape: White to almost white crystalline powder

Molecular weight: 266.55

Ref: 7W-GP9779

Clonidine Hydrochloride

CAS: 4205-91-8

Color and Shape: Neat

Ref: 86-MM0983.00

Clonidine hydrochloride

Controlled Product

CAS: 4205-91-8

Formula: C₉H₉Cl₂N₃·ClH

Color and Shape: Neat

Molecular weight: 266.55

Ref: 04-C11686810

GB 31660.6-2019 α2-Agonists Mixture 169 100 µg/mL in Methanol

Controlled Product

CAS: 4205-91-8, 59803-98-4, 64461-82-1, 73218-79-8, 7361-61-7

Color and Shape: Mixture

Ref: 04-A50000169ME

Clonidine hydrochloride

CAS: 4205-91-8

Formula: C₉H₉Cl₂N₃·HCl

Molecular weight: 266.55

Ref: 7W-GP5303

Clonidine Hydrochloride

Controlled Product

CAS: 4205-91-8

Stability Hygroscopic
Applications Labelled Clonidine. α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Roach, A.G., et al.: J. Pharmacol. Exp. Ther., 227, 421 (1983), Glassman, A.H., et al.: Science, 226, 864 (1984), Abounassif, A.M., et al.: Anal. Profiles Drug Subs. Excip., 21, 109 (1992),

Formula: C₉H₉Cl₂N₃·ClH

Color and Shape: Neat

Molecular weight: 266.55

Ref: TR-C587130

Clonidine hydrochloride

CAS: 4205-91-8

Clonidine hydrochloride is a drug used in the treatment of hypertension and other cardiac diseases. It belongs to the class of drugs called centrally acting alpha-2 adrenergic agonists. Clonidine hydrochloride is also used for its antihypertensive effects in patients with neurogenic orthostatic hypotension, diabetic neuropathy, and glomerular filtration rate. The long-term efficacy and safety profile of clonidine hydrochloride has been established in clinical trials that have shown it to be effective in reducing symptoms of chronic pain and opioid withdrawal, as well as improving quality of life. Clonidine hydrochloride may be administered orally or transdermally. Clonidine binds to both alpha-1 and alpha-2 adrenergic receptors, which are responsible for vasoconstriction, inhibition of renin secretion from the kidneys, decreased sympathetic nerve activity, and increased parasympathetic nerve activity. This drug also has a protective effect on bone cancer cells

Formula: C₉H₉Cl₂N₃•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 266.55 g/mol

Ref: 3D-FC20508