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CAS 4205-91-8

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Clonidine hydrochloride

Description:
Clonidine hydrochloride is a medication primarily used to treat high blood pressure and attention deficit hyperactivity disorder (ADHD). It is an alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to a decrease in sympathetic outflow and a subsequent reduction in heart rate and blood pressure. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets and transdermal patches. Clonidine hydrochloride has a molecular formula of C9H9ClN2HCl and a molecular weight of approximately 230.1 g/mol. Its pharmacological effects can also include sedation and analgesia, which is why it is sometimes used in managing withdrawal symptoms from opioids. However, it can cause side effects such as dry mouth, drowsiness, and hypotension. Due to its mechanism of action, careful monitoring is required when initiating or adjusting doses, especially in patients with cardiovascular conditions.
Formula:C9H10Cl3N3
InChI:InChI=1/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-4,9,13-14H,5H2;1H
InChI key:InChIKey=ZNIFSRGNXRYGHF-UHFFFAOYSA-N
SMILES:N(C1=C(Cl)C=CC=C1Cl)C=2NCCN2.Cl
Synonyms:
  • 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, hydrochloride (1:1)
  • 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride
  • 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
  • 2-Imidazoline, 2-(2,6-dichloroanilino)-, monohydrochloride
  • 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline hydrochloride
  • 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline monohydrochloride
  • Atensina
  • Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride
  • Capresin
  • Catapres
  • See more synonyms
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Found 17 products.
  • Clonidine Hydrochloride

    CAS:
    Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi
    Formula:C9H9Cl2N3·ClH
    Color and Shape:White Powder
    Molecular weight:264.99403
  • Clonidine Hydrochloride

    CAS:
    Formula:C9H9Cl2N3·HCl
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:266.55

    Ref: 3B-D1353

    1g
    48.00€
    5g
    132.00€
  • Clonidine hydrochloride, 98+%

    CAS:
    <p>Clonidine hydrochloride tablets are indicated in the treatment of hypertension. It has found new uses, including treatment of some types of neuropathic pain, opioid detoxification, sleep hyperhidrosis, anaesthetic use, and off-label, to counter the side effects of stimulant medications such as methy</p>
    Formula:C9H10Cl3N3
    Purity:98+%
    Molecular weight:266.55

    Ref: 02-J63707

    1g
    133.00€
    5g
    To inquire
  • Clonidine Hydrochloride

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR0983.00

    10mg
    302.00€
  • Ref: 61-AMP0983.00-01

    1ml
    71.00€
  • Clonidine hydrochloride

    CAS:
    Clonidine hydrochloride
    Formula:C9H9Cl2N3HCl
    Purity:99.8%
    Color and Shape:White
    Molecular weight:264.99403

    Ref: 47-85

    100mg
    242.00€
  • CLONIDINE HYDROCHLORIDE CRS

    CAS:
    CLONIDINE HYDROCHLORIDE CRS

    Ref: 41-C2400000

    25mg
    115.00€
  • Clonidine hydrochloride

    CAS:
    Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.
    Formula:C9H10Cl3N3
    Purity:99.16% - 99.86%
    Color and Shape:Solid
    Molecular weight:266.55
  • Clonidine hydrochloride

    CAS:
    Clonidine hydrochloride
    Purity:≥98%
    Molecular weight:266.55g/mol

    Ref: 54-BUP14908

    500mg
    51.00€
  • Clonidine HCl

    CAS:
    Formula:C9H9Cl2N3·HCl
    Color and Shape:White To Off-White Solid
    Molecular weight:230.09 36.46

    Ref: 4Z-C-258

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Clonidine hydrochloride, Ph. Eur. grade

    CAS:
    Formula:C9H9Cl2N3·HCl
    Purity:≤ 0.1%
    Color and Shape:White to almost white crystalline powder
    Molecular weight:266.55

    Ref: 7W-GP9779

    ne
    To inquire
  • Clonidine Hydrochloride

    CAS:
    Color and Shape:Neat

    Ref: 86-MM0983.00

    250mg
    1,597.00€
  • Clonidine hydrochloride

    Controlled Product
    CAS:
    Formula:C9H9Cl2N3·ClH
    Color and Shape:Neat
    Molecular weight:266.55

    Ref: 04-C11686810

    50mg
    86.00€
  • GB 31660.6-2019 α2-Agonists Mixture 169 100 µg/mL in Methanol

    Controlled Product
    CAS:
    Color and Shape:Mixture

    Ref: 04-A50000169ME

    1ml
    To inquire
  • Clonidine hydrochloride

    CAS:
    Formula:C9H9Cl2N3·HCl
    Molecular weight:266.55

    Ref: 7W-GP5303

    1g
    170.00€
    5g
    592.00€
  • Clonidine Hydrochloride

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications Labelled Clonidine. α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roach, A.G., et al.: J. Pharmacol. Exp. Ther., 227, 421 (1983), Glassman, A.H., et al.: Science, 226, 864 (1984), Abounassif, A.M., et al.: Anal. Profiles Drug Subs. Excip., 21, 109 (1992),<br></p>
    Formula:C9H9Cl2N3·ClH
    Color and Shape:Neat
    Molecular weight:266.55

    Ref: TR-C587130

    1g
    162.00€
    50mg
    113.00€
    100mg
    120.00€
  • Clonidine hydrochloride

    CAS:
    <p>Clonidine hydrochloride is a drug used in the treatment of hypertension and other cardiac diseases. It belongs to the class of drugs called centrally acting alpha-2 adrenergic agonists. Clonidine hydrochloride is also used for its antihypertensive effects in patients with neurogenic orthostatic hypotension, diabetic neuropathy, and glomerular filtration rate. The long-term efficacy and safety profile of clonidine hydrochloride has been established in clinical trials that have shown it to be effective in reducing symptoms of chronic pain and opioid withdrawal, as well as improving quality of life. Clonidine hydrochloride may be administered orally or transdermally. Clonidine binds to both alpha-1 and alpha-2 adrenergic receptors, which are responsible for vasoconstriction, inhibition of renin secretion from the kidneys, decreased sympathetic nerve activity, and increased parasympathetic nerve activity. This drug also has a protective effect on bone cancer cells</p>
    Formula:C9H9Cl2N3•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:266.55 g/mol

    Ref: 3D-FC20508

    25g
    291.00€
    50g
    410.00€
    100g
    486.00€
    250g
    To inquire
    500g
    To inquire