CAS 59803-98-4
:Brimonidine
Description:
Brimonidine is a selective alpha-2 adrenergic agonist primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It works by reducing intraocular pressure through decreased aqueous humor production and increased uveoscleral outflow. The chemical formula for Brimonidine is C11H10BrN5, and it features a brominated imidazoline structure, which contributes to its pharmacological activity. This compound is typically administered as an eye drop solution and is known for its efficacy in lowering eye pressure with a relatively favorable side effect profile. Brimonidine may cause mild ocular side effects such as redness or irritation, and systemic absorption can lead to effects like sedation or dry mouth. Its mechanism of action involves binding to alpha-2 adrenergic receptors, which modulates neurotransmitter release and reduces sympathetic outflow. Overall, Brimonidine is an important therapeutic agent in managing conditions associated with elevated intraocular pressure.
Formula:C11H10BrN5
InChI:InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
InChI key:InChIKey=XYLJNLCSTIOKRM-UHFFFAOYSA-N
SMILES:BrC=1C2=C(C=CC1NC=3NCCN3)N=CC=N2
Synonyms:- 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
- 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine
- 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
- 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-
- Agn 190342
- Bromoxidine
- Lyuksfen
- Uk 14,304
- Uk 14304-18
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Brimonidine
CAS:Formula:C11H10BrN5Purity:>98.0%(HPLC)(T)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:292.145-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-Yl)Quinoxalin-6-Amine
CAS:5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-Yl)Quinoxalin-6-AmineFormula:C11H10BrN5Purity:98%Molecular weight:292.13GB 31660.6-2019 α2-Agonists Mixture 169 100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:Mixture5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
CAS:Formula:C11H10BrN5Purity:98%Color and Shape:SolidMolecular weight:292.1346Brimonidine
CAS:Applications α2-Adrenoceptor agonist. Antiglaucoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Katz, L.J., et al.: Am. J. Ophthalmol., 127, 20 (1999); Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000);Formula:C11H10BrN5Color and Shape:NeatMolecular weight:292.13Brimonidine
CAS:Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P.Formula:C11H10BrN5Purity:99.62%Color and Shape:SolidMolecular weight:292.13Brimonidine
CAS:5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amineFormula:C11H10BrN5Purity:98%Molecular weight:292.13Brimonidine
CAS:Formula:C11H10BrN5Purity:≥ 98.0%Color and Shape:Light-yellow to yellow-green powderMolecular weight:292.13Brimonidine
CAS:M02627 - Brimonidine
Formula:C11H10BrN5Purity:95%Color and Shape:Solid, Yellow powderMolecular weight:292.1400146484375Brimonidine
CAS:Alpha-2-adrenoceptor agonist; reduces intraocular pressureFormula:C11H10BrN5Purity:Min. 95%Color and Shape:PowderMolecular weight:292.13 g/molBrimonidine L-tartrate
CAS:Brimonidine L-tartrate is a cyclase inhibitor that blocks the enzyme cyclic guanosine monophosphate (cGMP) phosphodiesterase. It has been shown to be effective in vivo in humans and has been shown to inhibit the production of neurotrophic factors in human HL-60 cells. Brimonidine L-tartrate is also effective as an anti-inflammatory agent and has long-term efficacy when used as a control analysis. This drug significantly reduced the rate constant of the 2-adrenergic receptor, which may lead to decreased risk of heart disease.Formula:C15H16BrN5O6Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:442.22 g/mol
