CAS 73218-79-8

Apraclonidine hydrochloride

Description:

Apraclonidine hydrochloride is a selective alpha-2 adrenergic agonist primarily used in ophthalmology to lower intraocular pressure in patients with glaucoma or ocular hypertension. As a hydrochloride salt, it is a white to off-white crystalline powder that is soluble in water and exhibits a pH range suitable for ophthalmic formulations. The compound works by reducing aqueous humor production and increasing uveoscleral outflow, thereby decreasing intraocular pressure. Apraclonidine has a relatively short duration of action, which necessitates multiple daily doses for effective management of eye pressure. It may cause side effects such as dry mouth, fatigue, and ocular irritation. Due to its pharmacological profile, it is often used in conjunction with other antiglaucoma medications to enhance therapeutic efficacy. Safety and efficacy have been established through clinical studies, making it a valuable option in the treatment of glaucoma. As with any medication, it is important for patients to follow their healthcare provider's instructions regarding its use.

Formula: C₉H₁₁Cl₃N₄

InChI: InChI=1/C9H10Cl2N4.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2,12H2,(H2,13,14,15);1H

InChI key: InChIKey=OTQYGBJVDRBCHC-UHFFFAOYSA-N

SMILES: N(C1=C(Cl)C=C(N)C=C1Cl)C=2NCCN2.Cl

Synonyms:

• 1,4-Benzenediamine, 2,6-dichloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
• 1,4-Benzenediamine, 2,6-dichloro-N¹-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)
• 1,4-Benzenediamine, 2,6-dichloro-N¹-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
• 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride
• 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride (1:1)
• 2-(4-Amino-2,6-dichloroanilino)-2-imidazoline hydrochloride
• Al 02145
• Alo 2145
• Aplonidine hydrochloride
• Iopidine
• P-aminoclonidine hydrochloride
• p-Aminoclonidine monohydrochloride
• Apraclonidine hydrochloride
• 1,4-Benzenediamine, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
• 1,4-Benzenediamine, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)
• Iopidine UD
• 3,5-dichloro-4-(2-imidazolidinylidenimino)anilinehydrochloride
• 2,6-dichloro-n(sup1)-(4,5-dihydro-1h-imidazol-2-yl)-1,4-benzenediaminemonoh
• nc14hydrochloride
• 2,6-dichloro-n(sup1)-(2-imidazolidinylidene)-1,4-benzenediaminehydrochlorid
• 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine Hydrochloride
• 2-(4-Amino-2,6-dichloroanilino)-2-imidazoline hydrochloride, Apraclonidine hydrochloride
• iopidineophthalmicsolution
• 2-[(4-AMINO-2,6-DICHLOROPHENYL)IMINO]IMIDAZOLIDINE MONOHYDROCHLORIDE
• 4-benzenediamine,2,6-dichloro-n(sup1)-(4,5-dihydro-1h-imidazol-2-yl)-mono
• 2-(4-amino-2,6-dichlorophenylimino)imidazolidinehydrochloride

Apraclonidine Hydrochloride

CAS: 73218-79-8

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₉H₁₀Cl₂N₄·HCl

Color and Shape: White Powder

Molecular weight: 244.02825

Ref: 45-1041609

Apraclonidine hydrochloride

CAS: 73218-79-8

Apraclonidine hydrochloride

Formula: C₉H₁₁Cl₃N₄

Purity: ≥98%

Molecular weight: 281.57

Ref: 54-BUP13679

Apraclonidine hydrochloride

Controlled Product

CAS: 73218-79-8

Formula: C₉H₁₀Cl₂N₄·ClH

Color and Shape: Neat

Molecular weight: 281.57

Ref: 04-C10292500

GB 31660.6-2019 α2-Agonists Mixture 169 100 µg/mL in Methanol

Controlled Product

CAS: 4205-91-8, 59803-98-4, 64461-82-1, 73218-79-8, 7361-61-7

Color and Shape: Mixture

Ref: 04-A50000169ME

Apraclonidine hydrochloride

CAS: 73218-79-8

Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist.

Formula: C₉H₁₁Cl₃N₄

Purity: 99.74%

Color and Shape: Solid

Molecular weight: 281.57

Ref: TM-T21371

Apraclonidine HCl

CAS: 73218-79-8

Formula: C₉H₁₀Cl₂N₄·HCl

Molecular weight: 245.11 36.46

Ref: 4Z-A-417001

Apraclonidine Hydrochloride

Controlled Product

CAS: 73218-79-8

Formula: C₉H₁₀Cl₂N₄·ClH

Color and Shape: Neat

Molecular weight: 281.57

Ref: TR-A729400

Apraclonidine HCl - Bio-X ™

CAS: 73218-79-8

Apraclonidine is an alpha adrenoreceptor agonist that is used in the treatment of raised intraocular pressure. This drug’s mechanism of action is not fully understood however, animal and human studies suggested that Apraclonidine reduces aqueous humor production and increases uveoscleral outflow.

Formula: C₉H₁₀Cl₂N₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 281.57 g/mol

Ref: 3D-BA164186

Apraclonidine hydrochloride

CAS: 73218-79-8

α2-adrenoceptor agonist; anti-glaucoma agent

Formula: C₉H₁₁Cl₃N₄

Purity: Min. 95%

Color and Shape: White Beige Powder

Molecular weight: 281.57 g/mol

Ref: 3D-FA17960

2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride

CAS: 73218-79-8

Formula: C₉H₁₁Cl₃N₄

Purity: ≥97%

Molecular weight: 281.57

Ref: 10-F362044