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CAS 4205-91-8

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Clonidine hydrochloride

Description:
Clonidine hydrochloride is a medication primarily used to treat high blood pressure and attention deficit hyperactivity disorder (ADHD). It is an alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to a decrease in sympathetic outflow and a subsequent reduction in heart rate and blood pressure. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets and transdermal patches. Clonidine hydrochloride has a molecular formula of C9H9ClN2HCl and a molecular weight of approximately 230.1 g/mol. Its pharmacological effects can also include sedation and analgesia, which is why it is sometimes used in managing withdrawal symptoms from opioids. However, it can cause side effects such as dry mouth, drowsiness, and hypotension. Due to its mechanism of action, careful monitoring is required when initiating or adjusting doses, especially in patients with cardiovascular conditions.
Formula:C9H10Cl3N3
InChI:InChI=1/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-4,9,13-14H,5H2;1H
InChI key:InChIKey=ZNIFSRGNXRYGHF-UHFFFAOYSA-N
SMILES:N(C1=C(Cl)C=CC=C1Cl)C=2NCCN2.Cl
Synonyms:
  • 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, hydrochloride (1:1)
  • 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride
  • 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
  • 2-Imidazoline, 2-(2,6-dichloroanilino)-, monohydrochloride
  • 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline hydrochloride
  • 2-[(2,6-Dichlorophenyl)amino]-2-imidazoline monohydrochloride
  • Atensina
  • Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride
  • Capresin
  • Catapres
  • See more synonyms
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