CAS 42116-76-7

Carnidazole

Description:

Carnidazole is a synthetic nitroimidazole derivative primarily used as an antiprotozoal and antibacterial agent. It exhibits a broad spectrum of activity against various protozoa, particularly those responsible for infections such as amoebiasis and giardiasis. The compound is characterized by its nitro group, which is crucial for its biological activity, as it is reduced within the anaerobic environment of the target organisms, leading to the generation of reactive intermediates that damage DNA and inhibit nucleic acid synthesis. Carnidazole is typically administered orally and is known for its relatively low toxicity profile compared to other agents in its class. Its pharmacokinetics involve absorption in the gastrointestinal tract, with metabolism occurring primarily in the liver. The substance is also noted for its potential side effects, which may include gastrointestinal disturbances and allergic reactions. Overall, Carnidazole represents an important therapeutic option in the treatment of certain parasitic infections, contributing to the broader field of antimicrobial chemotherapy.

Formula: C₈H₁₂N₄O₃S

InChI: InChI=1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)

InChI key: InChIKey=OVEVHVURWWTPFC-UHFFFAOYSA-N

SMILES: C(CNC(OC)=S)N1C(N(=O)=O)=CN=C1C

Synonyms:

• (2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl)carbamothioic acid O-methyl ester
• 1-(2-Ethylcarbamothioic acid O-methyl ester)-2-methyl-5-nitroimidazole
• Brn 0620260
• Carbamothioic acid, (2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)-, O-methyl ester
• Carbamothioic acid, N-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-, O-methyl ester
• Carnidazol
• Carnidazol [INN-Spanish]
• Carnidazole [USAN:INN:BAN]
• Carnidazolum
• Carnidazolum [INN-Latin]
• Me 108
• Nsc 293873
• O-Methyl (2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)carbamothioate
• O-Methyl (2-(2-methyl-5-nitroimidazol-1-yl)ethyl)thiocarbamate
• O-methyl [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]thiocarbamate
• R 25831
• Spartrix
• Unii-Rh5Ki819Jg
• 5-23-05-00062 (Beilstein Handbook Reference)

Carnidazole

CAS: 42116-76-7

Carnidazole

Purity: ≥98%

Molecular weight: 244.27g/mol

Ref: 54-BUP10797

PharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol

Controlled Product

CAS: 14885-29-1, 16773-42-5, 19387-91-8, 35175-14-5, 42116-76-7, 443-48-1, 4812-40-2, 551-92-8, 59-87-0, 67-45-8, 70028-95-4, 7681-76-7, 936-05-0

Color and Shape: Mixture

Ref: 04-A30000037ME

Carnidazole

CAS: 42116-76-7

Formula: C₈H₁₂N₄O₃S

Color and Shape: Neat

Molecular weight: 244.27

Ref: 04-C11044500

Carnidazole

CAS: 42116-76-7

Stability Hygroscopic
Applications Carnidazole is an anti-protozoal drug of nitroimidazole used in veterinary medicines. It is used in the trichomoniasis therapy in animals.
References Meneses-Marcel, A. et al.: Future Med. Chem., 10, 863 (2018); United States Food and Drug Administration: Fed. Reg., 54, 32336 (1989)

Formula: C₈H₁₂N₄O₃S

Color and Shape: Light Yellow

Molecular weight: 244.27

Ref: TR-C242220

Carnidazole

CAS: 42116-76-7

Carnidazole (ME-108) shows antiprotozoal activity and can be used in studies about the treatment of Trichomonas infection.

Formula: C₈H₁₂N₄O₃S

Purity: 99.81%

Color and Shape: Solid

Molecular weight: 244.27

Ref: TM-T20535