CAS 4316-98-7

6-Chloro-4,5-pyrimidinediamine

Description:

6-Chloro-4,5-pyrimidinediamine, with the CAS number 4316-98-7, is an organic compound characterized by its pyrimidine ring structure, which features two amino groups and a chlorine substituent. This compound typically appears as a solid and is soluble in polar solvents, reflecting its polar functional groups. The presence of the amino groups makes it a potential candidate for various chemical reactions, including nucleophilic substitutions and coupling reactions, which are valuable in the synthesis of pharmaceuticals and agrochemicals. Its chlorine atom introduces unique reactivity and can influence the compound's biological activity. 6-Chloro-4,5-pyrimidinediamine is of interest in medicinal chemistry due to its potential applications in drug development, particularly in targeting specific biological pathways. Safety data indicates that, like many nitrogen-containing compounds, it should be handled with care, as it may pose health risks if ingested or inhaled. Overall, this compound exemplifies the diverse chemistry of pyrimidine derivatives and their utility in various scientific fields.

Formula: C₄H₅ClN₄

InChI: InChI=1S/C4H5ClN4/c5-3-2(6)4(7)9-1-8-3/h1H,6H2,(H2,7,8,9)

InChI key: InChIKey=VNSFICAUILKARD-UHFFFAOYSA-N

SMILES: NC=1C(Cl)=NC=NC1N

Synonyms:

• 4,5-Diamino-6-chloropyrimidine
• 4,5-Pyrimidinediamine, 6-chloro-
• 4-Amino-6-Chloropyrimidin-5-Ylamine
• 4-Chloropyrimidine-5,6-diamine
• 5,6-Diamino-4-chloropyrimidine
• 6-Chloro-4,5-diaminopyrimidine
• 6-Chloro-4,5-pyrimidinediamine
• Ai3-52215
• Nsc 36907
• Pyrimidine, 4,5-diamino-6-chloro-
• 6-Chloropyrimidine-4,5-diamine

6-Chloropyrimidine-4,5-diamine

CAS: 4316-98-7

Formula: C₄H₅ClN₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Amber to Dark green powder to crystal

Molecular weight: 144.56

Ref: 3B-C3433

6-Chloro-4,5-diaminopyrimidine

CAS: 4316-98-7

Formula: C₄H₅ClN₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 144.5623

Ref: IN-DA003N5V

6-Chloropyrimidine-4,5-diamine

CAS: 4316-98-7

6-Chloropyrimidine-4,5-diamine

Formula: C₄H₅ClN₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 144.56229

Ref: 54-OR480730

4,5-Diamino-6-chloropyrimidine

Controlled Product

CAS: 4316-98-7

Applications A chlorinated diaminopyrimidine used in the preparation of various bioactive choloropurine derivatives.
References Suresh, M. et al.: Org. Chem. Ind. J., 6, 160 (2010);

Formula: C₄H₅ClN₄

Color and Shape: Neat

Molecular weight: 144.562

Ref: TR-D416275

4,5-Diamino-6-chloropyrimidine

CAS: 4316-98-7

4,5-Diamino-6-chloropyrimidine is a glycosidic compound that has been used for the optimization of drug targets. It has been shown to have antimalarial activity against Plasmodium falciparum in vitro and in vivo. 4,5-Diamino-6-chloropyrimidine binds to the amine groups on nucleotides, specifically purines (adenine and guanine), and amidates the 6-chloropurine ring. This makes it a potential candidate for use in chemotherapy. The structure of 4,5-diamino-6-chloropyrimidine was determined by NMR and mass spectroscopy analysis.

Formula: C₄H₅ClN₄

Purity: Min. 95%

Molecular weight: 144.56 g/mol

Ref: 3D-FD21470

6-Chloro-4,5-diaminopyrimidine

CAS: 4316-98-7

Formula: C₄H₅ClN₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 144.56

Ref: 10-F049092