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CAS 43210-67-9

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Fenbendazole

Description:
Fenbendazole is a broad-spectrum anthelmintic agent primarily used in veterinary medicine to treat parasitic infections in animals, particularly in livestock and pets. It belongs to the benzimidazole class of compounds, which are characterized by their ability to inhibit the polymerization of tubulin, thereby disrupting the microtubule formation necessary for cell division in parasites. Fenbendazole is typically administered orally and is known for its relatively low toxicity in mammals, making it a preferred choice for treating gastrointestinal parasites. The compound is poorly soluble in water but has better solubility in organic solvents, which can affect its bioavailability. Fenbendazole is often used in combination with other antiparasitic agents to enhance efficacy and broaden the spectrum of activity. Its effectiveness against various nematodes, cestodes, and some protozoa has made it a valuable tool in veterinary parasitology. Additionally, research has explored its potential applications in human medicine, particularly in cancer treatment, due to its ability to inhibit cellular proliferation.
Formula:C15H13N3O2S
InChI:InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
InChI key:InChIKey=HDDSHPAODJUKPD-UHFFFAOYSA-N
SMILES:S(C=1C=C2C(N=C(NC(OC)=O)N2)=CC1)C3=CC=CC=C3
Synonyms:
  • (5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester
  • 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole
  • Axilur
  • Carbamic acid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester
  • Carbamic acid, [5-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester
  • Febendazole
  • Fenbendazol
  • Fenbion
  • Hoe 881
  • Hoe-881V
  • See more synonyms
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