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CAS 443-48-1

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Metronidazole

Description:
Metronidazole is an antimicrobial and antiprotozoal medication primarily used to treat infections caused by anaerobic bacteria and certain parasites. It is classified as a nitroimidazole compound, characterized by its nitro group and imidazole ring structure. Metronidazole is effective against a variety of infections, including those caused by Trichomonas vaginalis, Giardia lamblia, and various anaerobic bacteria such as Bacteroides and Clostridium species. The substance is typically administered orally, topically, or intravenously, depending on the type and severity of the infection. Metronidazole exhibits good tissue penetration and is metabolized in the liver, with its metabolites being excreted primarily in urine. Common side effects may include gastrointestinal disturbances, headache, and a metallic taste. It is important to note that metronidazole should not be consumed with alcohol due to the potential for disulfiram-like reactions. Additionally, it is contraindicated in certain populations, such as pregnant women during the first trimester, due to potential risks. Overall, metronidazole is a crucial agent in the treatment of specific infectious diseases.
Formula:C6H9N3O3
InChI:InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChI key:InChIKey=VAOCPAMSLUNLGC-UHFFFAOYSA-N
SMILES:C(CO)N1C(N(=O)=O)=CN=C1C
Synonyms:
  • (2-Methyl-5-Nitro-1-Imidazolee
  • 1-(2'-Hydroxyethyl)-2-methyl-5-nitroimidazole
  • 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole
  • 1-(β-Hydroxyethyl)-2-methyl-5-nitroimidazole
  • 1-Hydroxyethyl-2-methyl-5-nitroimidazole
  • 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-
  • 2-(2-Methyl-5-Nitroimidazol-1-Yl)Ethanol
  • 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol
  • 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol
  • 2-(2-methyl-4-nitro-1H-imidazol-1-yl)ethanol
  • See more synonyms
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