CAS 480-19-3

Isorhamnetin

Description:

Isorhamnetin is a flavonoid, a type of polyphenolic compound, known for its antioxidant properties. It is a derivative of quercetin and is commonly found in various plants, including fruits, vegetables, and herbs. The chemical formula of isorhamnetin is C16H12O7, and it features a flavone backbone with hydroxyl and methoxy groups that contribute to its biological activity. Isorhamnetin exhibits a range of pharmacological effects, including anti-inflammatory, anti-cancer, and neuroprotective properties, making it a subject of interest in nutritional and medicinal research. Its antioxidant capacity helps in scavenging free radicals, thereby potentially reducing oxidative stress in cells. Additionally, isorhamnetin has been studied for its role in modulating various signaling pathways, which may influence metabolic processes and disease mechanisms. The compound is often extracted from natural sources for use in dietary supplements and functional foods, highlighting its significance in promoting health and wellness.

Formula: C₃₁H₄₂O₇

InChI: InChI=1/C16H12O7/c1-22-11-4-7(2-3-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3

InChI key: InChIKey=IZQSVPBOUDKVDZ-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1O)C3=CC(OC)=C(O)C=C3)=CC(O)=CC2O

Synonyms:

• 3'-Methoxyquercetin
• 3'-O-Methylquercetin
• 3,4',5,7-Tetrahydroxy-3'-methoxyflavone
• 3,4′,5,7-Tetrahydroxy-3′-methoxyflavone
• 3,5,7-Trihidroxi-2-(4-Hidroxi-3-Metoxifenil)-4-Benzopirona
• 3,5,7-Trihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-4-Benzopyrone
• 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyron
• 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
• 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
• 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
• 3-Methylquercetin
• 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
• Flavone, 3,4',5,7-tetrahydroxy-3'-methoxy-
• Flavone, 3,4′,5,7-tetrahydroxy-3′-methoxy-
• Isohamnetin
• Isorhamnetol
• Quercetin 3'-methyl ether
• Isorhamnetin
• C.I. 75680
• 3'-METHOXY-3,4',5,7-TETRAHYDROXYFLAVONE
• 3,5,7-trihydroxy-2-(4-hydroxy-3-metoxyphenyl)benzopyran-4-on
• 3'-METHOXY-3,5,7,4'-TETRAHYDROXYFLAVONE
• QUERCETIN-3-ORTHO-METHYLETHER
• QUERCETIN-3-METHYLETHER
• 3,4’,5,7-tetrahydroxy-3’-methoxy-flavon
• 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-on
• 3’-methoxy-3,4’,5,7-tetrahydroxy-flavon
• 3,5,7,4'-TETRAHYDROXY-3'-METHOXYFLAVONE
• 2-(3-methoxy-4-hydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on
• 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one

Isorhamnetin

CAS: 480-19-3

Formula: C₁₆H₁₂O₇

Purity: >95.0%(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 316.27

Ref: 3B-I1068

Isorhamnetin

CAS: 480-19-3

Isorhamnetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₆H₁₂O₇

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 316.28

Ref: 11-1120S

Isorhamnetin

CAS: 480-19-3

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₁₆H₁₂O₇

Color and Shape: Light Yellow Powder

Molecular weight: 316.0583

Ref: 45-1351800

3,5,7-Trihydroxy-2-(4-hydroxy-3-metoxyphenyl)benzopyran-4-one

CAS: 480-19-3

Formula: C₁₆H₁₂O₇

Purity: 97%

Color and Shape: Solid

Molecular weight: 316.2623

Ref: IN-DA0037F1

Isorhamnetin

CAS: 480-19-3

Isorhamnetin

Formula: C₁₆H₁₂O₇

Purity: 99.30% (lc-ms) (Typical Value in Batch COA)

Color and Shape: Solid

Molecular weight: 316.26227

Ref: 54-BISN0190

Isorhamnetin

CAS: 480-19-3

Formula: C₁₆H₁₂O₇

Purity: ≥ 98.0%

Color and Shape: Yellow powder

Molecular weight: 316.26

Ref: 7W-GP5169

Isorhamnetin

CAS: 480-19-3

Isorhamnetin

Formula: C₁₆H₁₂O₇

Purity: ≥90%

Molecular weight: 316.26

Ref: 54-BUP12266

Isorhamnetin

CAS: 480-19-3

Formula: C₁₆H₁₂O₇

Molecular weight: 316.27

Ref: 4Z-Q-0513

Isorhamnetin

CAS: 480-19-3

Formula: C₁₆H₁₂O₇

Color and Shape: Neat

Molecular weight: 316.26

Ref: 04-C14473200

Isorhamnetin (Standard)

CAS: 480-19-3

Isorhamnetin (Standard) is a reference standard for research and analysis in studies involving Isorhamnetin. Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of ox-LDL-mediated intracellular signaling pathway (p38MAPK activation, NF-kappaB nuclear translocation, eNOS expression) and the antioxidant activity of isorhamnetin. Isorhamnetin prevents endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II. Isorhamnetin appears to be a potent drug against esophageal cancer due to it's in vitro potential to not only inhibit proliferation but also induce apoptosis of Eca-109 cells.

Formula: C₁₆H₁₂O₇

Molecular weight: 316.26

Ref: TM-TMSM-3032

Isorhamnetin

CAS: 480-19-3

Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has anti-adipogenic, cardioprotective, anti-tumor, and antioxidant activities. it inhibits the H(2)O(2)-induced activation of the intrinsic apoptotic pathway via ROS scavenging and ERK inactivation, it inhibits NF-κB signaling. Isorhamnetin prevents angiotensin II (AngII)-induced endothelial dysfunction by inhibiting the overexpression of p47(phox) and the subsequent increases O2-production, resulting in increased nitric oxide bioavailability.

Formula: C₁₆H₁₂O₇

Purity: 95%~99%

Molecular weight: 316.265

Ref: BP-BP0794

Isorhamnetin

CAS: 480-19-3

Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.

Formula: C₁₆H₁₂O₇

Purity: 99.20% - >99.99%

Color and Shape: Solid

Molecular weight: 316.26

Ref: TM-T2836

Isorhamnetin

CAS: 480-19-3

Oxygen-heterocyclic compound

Formula: C₁₆H₁₂O₇

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 316.27

Ref: 5G-89314

3'-O-Methyl-d3 Quercetin

Controlled Product

CAS: 480-19-3

Applications 3'-O-Methyl-d3 Quercetin is the labeled analogue of 3'-O-Methyl Quercetin (M326575), a metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways.
References Duenas, M. et al.: Eur. Food Res. Technol., 232, 103 (2011); Ameho, C.K. et al.: J. Nutrit. Biochem., 19, 467 (2008); Angeloni, C. et al.: Biochimie, 89, 73 (2007)

Formula: C₁₆D₃H₉O₇

Color and Shape: Neat

Molecular weight: 319.281

Ref: TR-M326577

3'-O-Methyl Quercetin

CAS: 480-19-3

Applications A metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways.
References Duenas, M. et al.: Eur. Food Res. Technol., 232, 103 (2011); Ameho, C.K. et al.: J. Nutrit. Biochem., 19, 467 (2008); Angeloni, C. et al.: Biochimie, 89, 73 (2007);

Formula: C₁₆H₁₂O₇

Color and Shape: Neat

Molecular weight: 316.26

Ref: TR-M326575

Isorhamnetin

CAS: 480-19-3

Isorhamnetin is a naturally occurring flavonoid, which is isolated from various plant sources such as fruits, vegetables, and medicinal herbs like Ginkgo biloba. As a member of the flavonoid family, it is primarily derived from the glycosylation and methylation of quercetin. The mode of action of isorhamnetin is mainly attributed to its potent antioxidant capabilities. It scavenges reactive oxygen species and inhibits oxidative stress, which may lead to beneficial effects in preventing cellular damage.

Formula: C₁₆H₁₂O₇

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 316.26 g/mol

Ref: 3D-FI09252

Isorhamnetin

CAS: 480-19-3

3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one

Formula: C₁₆H₁₂O₇

Purity: 97%

Molecular weight: 316.26

Ref: IN-DG20976

ISORHAMNETIN

CAS: 480-19-3

Purity: 97%

Molecular weight: 316.2650146

Ref: 10-F808044