Isorhamnetin

CAS: 480-19-3

Ref. TM-T2836

Product Information

• Name: Isorhamnetin
• Synonyms: 3-methylquercetin, 3'-Methylquercetin, Isorhamnetol, 3'-Methoxyquercetin, 3'-Methoxyquercetin, 3'-O-Methylquercetin, 3,4',5,7-Tetrahydroxy-3'-methoxyflavone, 3,4′,5,7-Tetrahydroxy-3′-methoxyflavone, 3,5,7-Trihidroxi-2-(4-Hidroxi-3-Metoxifenil)-4-Benzopirona, 3,5,7-Trihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-4-Benzopyrone, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyron, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one, 3-Methylquercetin, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, Flavone, 3,4',5,7-tetrahydroxy-3'-methoxy-, Flavone, 3,4′,5,7-tetrahydroxy-3′-methoxy-, Isohamnetin, Isorhamnetol, Quercetin 3'-methyl ether
• CAS: 480-19-3

Description

Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of ox-LDL-mediated intracellular signaling pathway (p38MAPK activation, NF-kappaB nuclear translocation, eNOS expression) and the antioxidant activity of isorhamnetin. Isorhamnetin prevents endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II. Isorhamnetin appears to be a potent drug against esophageal cancer due to it's in vitro potential to not only inhibit proliferation but also induce apoptosis of Eca-109 cells.

• Brand: Targetmol

Chemical properties

• Molecular weight: 316.26
• Formula: C₁₆H₁₂O₇
• Purity: 98.97%
• Color/Form: Solid