CAS 481-42-5

Plumbagin

Description:

Plumbagin, with the CAS number 481-42-5, is a naturally occurring naphthoquinone compound primarily derived from the roots of the plant *Plumbago* species, particularly *Plumbago zeylanica*. It is characterized by its yellow to orange crystalline appearance and has a molecular formula of C11H8O3. Plumbagin exhibits a range of biological activities, including antimicrobial, anticancer, and antioxidant properties, making it of interest in pharmacological research. The compound is known to interact with various cellular pathways, potentially influencing apoptosis and cell proliferation. Additionally, plumbagin has been studied for its ability to inhibit certain enzymes and its role in traditional medicine. Its solubility is generally higher in organic solvents than in water, which is a common trait for many organic compounds. However, due to its reactive nature, plumbagin can undergo oxidation and other chemical transformations, which may affect its stability and efficacy in various applications. Overall, plumbagin represents a significant compound in both natural product chemistry and medicinal research.

Formula: C₁₁H₈O₃

InChI: InChI=1/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

InChI key: InChIKey=VCMMXZQDRFWYSE-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=C1C)=C(O)C=CC2

Synonyms:

• 1,4-Naphthalenedione, 5-hydroxy-2-methyl-
• 1,4-Naphthoquinone, 5-hydroxy-2-methyl-
• 2-Methyl-5-hydroxy-1,4-naphthalenedione
• 2-Methyl-5-hydroxy-1,4-naphthoquinone
• 2-Methyljuglone
• 5-Hydroxy-2-Methylnaphthalene-1,4-Dione
• 5-Hydroxy-2-methyl-1,4-naphthalenedione
• 5-Hydroxy-2-methyl-1,4-naphthoquinone
• NSC 236613
• NSC 688284
• Plumbagin from Plumbago indica
• Plumbagin,95%
• Plumbagine
• Plumbagone
• Plumbagin
• Plumbagin, 99+%
• Ophioxylin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone, Plumbagin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone
• PLUMBAGIN(RG)
• PLUMBAGIN PRACTICAL GRADE
• SPECS AP-782/41885488
• RARECHEM BW GA 0426
• 5-hydroxy-2-methyl-4-naphthoquinone
• plumbapin
• 5-HYDROXY-2-METHYL-1,4-NAPTHOQUINONE
• Plumbagin (natural)
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene
• PLANT STEROLS KIT
• 5-hydroxy-2-methyl-4-naphthalenedione
• PLUMBAGIN FROM FROM PLUMBAGO INDICA
• PLUMBAGAN

Plumbagin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: Orange to Brown powder to crystal

Molecular weight: 188.18

Ref: 3B-P1139

Plumbagin

CAS: 481-42-5

Plumbagin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₁H₈O₃

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 188.18

Ref: 11-0444

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 188.1794

Ref: IN-DA003TTF

Plumbagin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Molecular weight: 188.18

Ref: 7W-GL1138

Plumbagin

CAS: 481-42-5

Plumbagin

Purity: ≥98%

Molecular weight: 188.18g/mol

Ref: 54-BUP11118

plumbapin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purity: 95%~99%

Molecular weight: 188.182

Ref: BP-BP1113

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

5-Hydroxy-2-methylnaphthalene-1,4-dione

Formula: C₁₁H₈O₃

Purity: 95%

Color and Shape: reddish orange/tan powder

Molecular weight: 188.18g/mol

Ref: 54-OR1174

Plumbagin

CAS: 481-42-5

Plumbagin, a yellow dye from naphthoquinone, is isolated from Plumbago and found in Drosera, Nepenthes, and black walnut drupe.

Formula: C₁₁H₈O₃

Purity: 99.7% - 99.95%

Color and Shape: Soild

Molecular weight: 188.18

Ref: TM-T2841

Plumbagin

CAS: 481-42-5

Plumbagin

Formula: C₁₁H₈O₃

Purity: By hplc: 99.4% by area (210nm) (Typical Value in Batch COA)

Color and Shape: reddish orange/tan powder

Molecular weight: 188.18g/mol

Ref: 54-BIDF1037

Plumbagin

CAS: 481-42-5

Quinone

Formula: C₁₁H₈O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 188.18

Ref: 5G-80267

Plumbagin

CAS: 481-42-5

Applications Plumbagin induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Formula: C₁₁H₈O₃

Color and Shape: Dark Orange

Molecular weight: 188.18

Ref: TR-P627000

Plumbagin

CAS: 481-42-5

Plumbagin is a quinonoid compound, which is a secondary metabolite found in the roots of Plumbago species. This compound is characterized by its naphthoquinone structure, which is responsible for its diverse biological activities. Plumbagin exerts its effects primarily through the generation of reactive oxygen species (ROS), modulation of cellular signaling pathways, and inhibition of specific enzyme functions, such as topoisomerases. These actions result in the modulation of cell proliferation, apoptosis, and inflammation, making Plumbagin a compound of interest for various biomedical applications.

Formula: C₁₁H₈O₃

Purity: Min. 95%

Color and Shape: Orange Powder

Molecular weight: 188.18 g/mol

Ref: 3D-FP13778

5-Hydroxy-2-methyl-[1,4]naphthoquinone

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purity: 98%

Color and Shape: No data available.

Molecular weight: 188.182

Ref: 10-F032384

Plumbagin-d3

Controlled Product

CAS: 481-42-5

Applications Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Formula: C₁₁H₅D₃O₃

Color and Shape: Neat

Molecular weight: 191.2

Ref: TR-P627002