CAS 496-76-4

Isobarbituric acid

Description:

Isobarbituric acid, with the CAS number 496-76-4, is a chemical compound that belongs to the class of barbiturates, which are derivatives of barbituric acid. It is characterized by its structural formula, which features a pyrimidine ring with two carbonyl groups and an amino group. Isobarbituric acid is typically a white crystalline solid that is soluble in water and exhibits weak acidic properties. Its molecular structure allows it to participate in various chemical reactions, making it of interest in both pharmaceutical and biochemical research. The compound is known for its potential applications in the synthesis of other organic compounds and may also serve as an intermediate in the production of certain pharmaceuticals. Additionally, isobarbituric acid can exhibit biological activity, although its specific effects and mechanisms of action may vary. Safety data indicates that, like many chemical substances, it should be handled with care, following appropriate safety protocols to minimize exposure and risk.

Formula: C₄H₄N₂O₃

InChI: InChI=1S/C4H4N2O3/c7-2-1-5-4(9)6-3(2)8/h1H2,(H2,5,6,8,9)

InChI key: InChIKey=FQXOOGHQVPKHPG-UHFFFAOYSA-N

SMILES: O=C1C(=O)CNC(=O)N1

Synonyms:

• 1,3-Diazinane-2,4,5-trione
• 2,4,5(3H)-Pyrimidinetrione, dihydro-
• 5-Hydroxyuracil
• 5-hydroxypyrimidine-2,4(1H,3H)-dione
• Dihydro-2,4,5(3H)-pyrimidinetrione
• Isobarbituric acid
• NSC 95958
• dihydropyrimidine-2,4,5(3H)-trione

Isobarbituric Acid

CAS: 496-76-4

Formula: C₄H₄N₂O₃

Purity: >97.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 128.09

Ref: 3B-I0310

2,4,5-Trihydroxypyrimidine, 98%

CAS: 496-76-4

2,4,5-Trihydroxypyrimidine studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin. It acts as an antagonist of uracil in the growth of Lactobacillus casei. This Thermo Scientific Chemicals bran

Formula: C₄H₄N₂O₃

Purity: 98%

Color and Shape: Powder, White to pale cream

Molecular weight: 128.09

Ref: 02-B23320

FLUOROURACIL IMPURITY B CRS

CAS: 496-76-4

FLUOROURACIL IMPURITY B CRS

Formula: C₄H₄N₂O₃

Molecular weight: 128.0862

Ref: 41-Y0000763

Fluorouracil Related Compound B (Dihydropyrimidine-2,4,5(3H)-trione)

CAS: 496-76-4

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoi

Formula: C₄H₄N₂O₃

Color and Shape: White Powder

Molecular weight: 128.02219

Ref: 45-1279021

Isobarbituric Acid

CAS: 496-76-4

Formula: C₄H₄N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 128.0862

Ref: IN-DA003R2D

Dihydropyrimidine-2,4,5(3H)-trione (Isobarbituric Acid; 5-Hydroxyuracil)

CAS: 496-76-4

Color and Shape: Neat

Ref: 86-MM0593.01

Fluorouracil EP Impurity B

CAS: 496-76-4

Formula: C₄H₄N₂O₃

Molecular weight: 128.09

Ref: 4Z-F-539

Dihydropyrimidine-2,4,5(3H)-trione

CAS: 496-76-4

Purity: 98%

Molecular weight: 128.02

Ref: 10-F570511

Isobarbituric acid

CAS: 496-76-4

Isobarbituric acid is a glycosylase that cleaves the bond between the amino group and the hydroxyl group of uridine in DNA. It has been shown to react with nucleophilic groups at neutral pH, such as an amine or hydroxyl group. Isobarbituric acid can be used to measure oxidative damage to DNA. This compound is reactive and sensitive to UV light, which makes it useful for detecting damaged DNA. Isobarbituric acid has been shown to induce neuronal death in rodents by interfering with dendritic spine formation.

Formula: C₄H₄N₂O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 128.09 g/mol

Ref: 3D-FI24655

Isobarbituric Acid

CAS: 496-76-4

Impurity Fluorouracil EP Impurity B; Fluorouracil USP Related Compound B
Applications A 5-hydroxy derivative of the nucleobase Uracil (U801000) and an isomer of Barbituric Acid (B118650). Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin. Fluorouracil EP Impurity B. Fluorouracil USP Related Compound B
References Varatharasa T. et al.: Chem. Comm., 3, 400 (2005); Jaruga, P. et al.: Nucleic Acid Res., 24, 1389 (1996); Rodriguez, H. et al.: Adv. Exp. Med. Biol., 534, 129 (2003);

Formula: C₄H₄N₂O₃

Color and Shape: Neat

Molecular weight: 128.09

Ref: TR-I780030

Fluorouracil EP Impurity B

CAS: 496-76-4

Formula: C₄H₄N₂O₃

Molecular weight: 128.1

Ref: ST-EA-CP-F32002