CAS 50-18-0

cyclophosphamide

Description:

Cyclophosphamide is a synthetic alkylating agent primarily used in chemotherapy for various cancers, including lymphomas and leukemias. It belongs to the class of nitrogen mustards and is characterized by its ability to interfere with DNA replication, leading to cell death, particularly in rapidly dividing cells. Cyclophosphamide is a prodrug, meaning it requires metabolic activation in the liver to convert into its active form, which exerts its cytotoxic effects. The compound is typically administered intravenously or orally and is known for its immunosuppressive properties, making it useful in treating autoimmune diseases as well. Its chemical structure includes a phosphoramide group, which contributes to its reactivity. Cyclophosphamide can cause a range of side effects, including nausea, vomiting, and potential long-term risks such as secondary malignancies. Due to its potent effects, careful monitoring and dosage adjustments are essential during treatment. Overall, cyclophosphamide remains a critical agent in oncology and immunology, highlighting its significance in medical therapeutics.

Formula: C₇H₁₅Cl₂N₂O₂P

InChI: InChI=1/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key: InChIKey=CMSMOCZEIVJLDB-UHFFFAOYSA-N

SMILES: N(CCCl)(CCCl)P1(=O)NCCCO1

Synonyms:

• (RS)-Cyclophosphamide
• 1-(Bis(2-Chloroethyl)Amino)-1-Oxo-2-Aza-5-Oxaphosphoridine
• 2-(Bis(2-Chloroethyl)Amino)-1,3,2-Oxazaphosphorinane 2-Oxide
• 2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide
• 2-(Di(2-Chloroethyl)Amino)-1-Oxa-3-Aza-2-Phosphacyclohexane 2-Oxide
• 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
• 2H-1,3,2-Oxazaphosphorin, 2-amine, N,N-bis((2-chloroethyl)tetrahydro-, 2-oxide
• 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
• Asta B 518
• B 518
• Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
• CP
• CPA
• CTX
• CY
• Cb 4564
• Ciclofosfamida
• Clafen
• Claphene
• Cycloblastin
• Cyclocel
• Cyclophosphamid
• Cyclophosphamide Sterile
• Cyclophosphamidum
• Cyclophosphan
• Cyclophosphane
• Cyclostin
• Cycloxan
• Cycrame
• Cydoxan
• Cyphos
• Cytophosphan
• Cytophosphane
• Cytoxan
• Eldamide
• Endoxan
• Endoxan R
• Endoxan-Asta
• Endoxana
• Endoxanal
• Endoxane
• Enduxan
• Genoxal
• Hexadrin
• Ledoxan
• Mitoxan
• N,N-Bis(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
• N,N-Bis(β-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide
• N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide hydrate (1:1)
• Nci C04900
• Neophos
• Neosar
• Neosar (antineoplastic)
• Nsc 26271
• Oncomide
• Procytox
• Revimmune
• Semdoxan
• Sendoxan
• Senduxan
• Sk 20501
• Zyklophosphamid
• 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide, monohydrate
• ASTA
• Cyclophosphoramide
• (Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate

Cyclophosphamide Monohydrate

CAS: 50-18-0, 6055-19-2

Formula: C₇H₁₅Cl₂N₂O₂P·H₂O

Purity: >98.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 279.10

Ref: 3B-C2236

Cyclophosphamide

CAS: 50-18-0

Cyclophosphamide

Purity: ≥98%

Molecular weight: 261.09g/mol

Ref: 54-BUP16030

Cyclophosphamide

CAS: 50-18-0

Formula: C₇H₁₅Cl₂N₂O₂P

Molecular weight: 261.09

Ref: 4Z-C-10246

Cyclophosphamide

CAS: 50-18-0

Purity: ¡Ý98.0%

Molecular weight: 261.08

Ref: 10-F979812

Cyclophosphamide

CAS: 50-18-0

Cyclophosphamide is an alkylating agent type of anti-tumor drug, and its main target is DNA. High-Quality, Low-Cost!

Formula: C₇H₁₅Cl₂N₂O₂P

Purity: 99.42% - >99.99%

Color and Shape: Liquefies On Loss Of Its Water Of Crystallization

Molecular weight: 261.09

Ref: TM-T0707L