CAS 50370-12-2: Cefadroxil
Description:Cefadroxil is a first-generation cephalosporin antibiotic, primarily used to treat bacterial infections. It is characterized by its broad-spectrum activity against various gram-positive and some gram-negative bacteria. The chemical structure of cefadroxil includes a beta-lactam ring, which is essential for its antibacterial activity, as it inhibits bacterial cell wall synthesis. Cefadroxil is typically administered orally and is known for its good absorption and bioavailability. It is often prescribed for conditions such as urinary tract infections, skin infections, and respiratory tract infections. The substance is generally well-tolerated, though potential side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. Its pharmacokinetics involve renal excretion, necessitating dosage adjustments in patients with impaired kidney function. As with all antibiotics, it is crucial to complete the prescribed course to prevent the development of antibiotic resistance.
Formula:C16H17N3O5S
InChI:InChI=1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1
InChI key:InChIKey=BOEGTKLJZSQCCD-UEKVPHQBSA-N
SMILES:O=C(O)C1=C(C)CSC2N1C(=O)C2NC(=O)C(N)C3=CC=C(O)C=C3
- Synonyms:
- (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, [6R-[6α,7β(R*)]]-
- <span class="text-smallcaps">D</span>-Cefadroxil
- Bidocef
- Bl-S 578
- Cefadrox
- Cefadroxil Anhydrous
- Cefadroxilo
- See more synonyms
- Cefadur
- Cephadroxil
- Cipadur
- D-Cefadroxil
- Evacef
- Helicef
- Ibidroxil
- Neucef
- Oracefal
- Roxil
- S 578
- Sumacef
- Ultracef
- Cefadroxil