CAS 508233-74-7
:Vortioxetine
Description:
Vortioxetine is an antidepressant medication primarily used to treat major depressive disorder. It is classified as a serotonin modulator and stimulator, which means it influences various serotonin receptors in the brain, enhancing serotonin levels and activity. The chemical formula for vortioxetine is C18H22N2S, and it features a unique structure that includes a phenyl ring, a piperazine moiety, and a thiophene ring. This compound exhibits a dual mechanism of action: it not only inhibits the reuptake of serotonin but also acts as an agonist or antagonist at specific serotonin receptors, contributing to its therapeutic effects. Vortioxetine is generally well-tolerated, with a side effect profile that may include nausea, constipation, and sexual dysfunction. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring during treatment.
Formula:C18H22N2S
InChI:InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3
InChI key:InChIKey=YQNWZWMKLDQSAC-UHFFFAOYSA-N
SMILES:S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3
Synonyms:- 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
- 1-(2-(2.4-Dimeethylphenylthio)Pheny1) Piperazine
- 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine
- Brintellix
- Lu AA 21004
- Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-
- Trintellix
- Vortioxetine
- Vortioxetine 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
- Vortioxetine(Lu AA21004)
- Trintellix (vortioxetine)
- Vortioxetine, >=99%
- 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE-HCL
- See more synonyms
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Found 11 products.
Vortioxetine
CAS:<p>Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.</p>Formula:C18H22N2SPurity:99.34% - 99.34%Color and Shape:SolidMolecular weight:298.45Vortioxetine
CAS:Controlled Product<p>Applications Vortioxetine can be used in biological study of effectiveness of long term vortioxetine treatment of patients with major depressive disorder.<br>References Vieta, E., et al.: Eur Neuropsychopharm (2017)<br></p>Formula:C18H22N2SColor and Shape:NeatMolecular weight:298.45Vortioxetine Hydrobromide-D8
CAS:Controlled Product<p>Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formula:C18D8H14N2S·BrHColor and Shape:Off White PowderMolecular weight:387.4069Vortioxetine
CAS:Controlled Product<p>Vortioxetine is a serotonin modulator and reuptake inhibitor which appears to be much more potent on serotonin reuptake inhibition and 5-HT3 receptor antagonism than other interactions with the 5-HT receptor family. This drug binds selectively to 5-HT receptors and inhibits the activity of serotonin reuptake transporters on presynaptic neurons, thereby increasing serotonin concentrations in the brain. It is used for the treatment of major depressive disorder (MDD)and has also been shown to be effective against depression-related symptoms such as sleep disturbances, appetite disturbance, and weight change. Vortioxetine has also been demonstrated to suppress glioblastoma in both ex vivo human tissue samples and in mice. This may indicate vortioxetine signalling cascade activation supresses cancer cell division, and could constitute an effective part of a treatment regime for glioblastoma patients.</p>Formula:C18H22N2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:298.45 g/mol
