CAS 960203-27-4
:Vortioxetine hydrobromide
Description:
Vortioxetine hydrobromide is a pharmacological compound primarily used as an antidepressant. It functions as a serotonin modulator and stimulator, influencing various serotonin receptors and the reuptake of serotonin in the brain. This unique mechanism of action contributes to its efficacy in treating major depressive disorder. The substance is characterized by its molecular formula, which reflects its complex structure, and it typically appears as a white to off-white crystalline powder. Vortioxetine hydrobromide is soluble in water and exhibits stability under standard storage conditions. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing in clinical settings. Common side effects may include nausea, dizziness, and sexual dysfunction, which are important considerations in patient management. As with any medication, it is essential to monitor for potential interactions with other drugs and to assess individual patient responses to therapy. Overall, vortioxetine hydrobromide represents a significant advancement in the treatment of depression, offering a distinct approach compared to traditional antidepressants.
Formula:C18H22N2S·HBr
InChI:InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1H
InChI key:InChIKey=VNGRUFUIHGGOOM-UHFFFAOYSA-N
SMILES:S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3.Br
Synonyms:- Lu AA 21004 hydrobromide
- Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-, hydrobromide (1:1)
- Vortioxetine hydrobromide
- Vothiaxetine
- 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide
- Vortioxetine (Lu AA21004) HBr
- 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine hydrobromide
- Lu AA21004 (HBr)
- 1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine, hydrobromid
- Vortioxetine HBr
- Vortioxetine (Lu AA21004) hydrobroMide
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Vortioxetine Hydrobromide
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:C18H22N2S·HBrColor and Shape:White Crystalline PowderMolecular weight:298.15037Vortioxetine hydrobromide
CAS:Vortioxetine hydrobromideFormula:C18H22N2S·HBrPurity:99.5%Molecular weight:379.361-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine Hydrobromide
CAS:1-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine HydrobromideFormula:C18H23BrN2SPurity:0.99Molecular weight:379.36Vortioxetine hydrobromide
CAS:Formula:C18H23BrN2SPurity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:379.36Vortioxetine.HBr, 1mg/ml in Methanol (as free base)
CAS:Formula:C18H22N2S·BrHColor and Shape:ColourlessMolecular weight:379.358Vortioxetine Hydrobromide
CAS:Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)Formula:C18H22N2S·BrHColor and Shape:NeatMolecular weight:379.358Vortioxetine Hydrobromide-D8
CAS:Controlled ProductApplications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)Formula:C18D8H14N2S·BrHColor and Shape:NeatMolecular weight:387.407N-Nitroso-Vortioxetine-D8
CAS:Controlled ProductFormula:C18H13D8N3OSColor and Shape:NeatMolecular weight:335.49Vortioxetine Hydrobromide (1 mg/mL in Methanol)
CAS:Formula:C18H22N2S·BrHColor and Shape:Single SolutionMolecular weight:379.358Vortioxetine hydrobromide
CAS:Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33Formula:C18H23BrN2SPurity:98.85% - 99.98%Color and Shape:White SolidMolecular weight:379.361-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine hydrobromide
CAS:1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine hydrobromideFormula:C18H23BrN2SPurity:99%Molecular weight:379.361-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide
CAS:Controlled Product1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide is an atypical antidepressant that is used for the treatment of major depressive disorder. It has been shown to be effective in animal models of depression and in clinical trials with humans. 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide blocks the serotonin 5HT1B receptor subtype, which is responsible for regulating mood and emotional response. This drug does not block the 5HT1A or 5HT2 receptors, so it does not cause some of the side effects associated with selective serotonin reuptake inhibitors (SSRIs). In addition, 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide has a chemical stability that lasts longer than other drugs in its class.Formula:C18H22N2S·HBrPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:379.36 g/molVortioxetine hydrobromide
CAS:Formula:C18H23BrN2SPurity:95%Color and Shape:SolidMolecular weight:379.361-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine hydrobromide
CAS:Formula:C18H23BrN2SPurity:95%Color and Shape:SolidMolecular weight:379.3576
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