CAS 508233-74-7

Vortioxetine

Description:

Vortioxetine is an antidepressant medication primarily used to treat major depressive disorder. It is classified as a serotonin modulator and stimulator, which means it influences various serotonin receptors in the brain, enhancing serotonin levels and activity. The chemical formula for vortioxetine is C18H22N2S, and it features a unique structure that includes a phenyl ring, a piperazine moiety, and a thiophene ring. This compound exhibits a dual mechanism of action: it not only inhibits the reuptake of serotonin but also acts as an agonist or antagonist at specific serotonin receptors, contributing to its therapeutic effects. Vortioxetine is generally well-tolerated, with a side effect profile that may include nausea, constipation, and sexual dysfunction. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring during treatment.

Formula: C₁₈H₂₂N₂S

InChI: InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3

InChI key: InChIKey=YQNWZWMKLDQSAC-UHFFFAOYSA-N

SMILES: S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3

Synonyms:

• 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
• 1-(2-(2.4-Dimeethylphenylthio)Pheny1) Piperazine
• 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine
• Brintellix
• Lu AA 21004
• Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-
• Trintellix
• Vortioxetine
• Vortioxetine 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
• Vortioxetine(Lu AA21004)
• Trintellix (vortioxetine)
• Vortioxetine, >=99%
• 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE-HCL

Lu AA 21004

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Purity: >95.0%(HPLC)(T)

Molecular weight: 298.45

Ref: 3B-V0200

Vortioxetine

CAS: 508233-74-7

Vortioxetine

Formula: C₁₈H₂₂N₂S

Purity: 98%

Molecular weight: 298.45

Ref: 54-OR1028064

Vortioxetine

CAS: 508233-74-7

Vortioxetine

Formula: C₁₈H₂₂N₂S

Purity: 99.5%

Color and Shape: Solid

Molecular weight: 298.45

Ref: 54-BUP15037

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Color and Shape: Off-White Solid

Molecular weight: 298.45

Ref: 4Z-V-043001

Vortioxetine (Standard)

CAS: 508233-74-7

Vortioxetine (Standard) is a reference standard for research and analysis in studies involving Vortioxetine. Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.45

Ref: TM-TMSM-3548

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Color and Shape: Neat

Molecular weight: 298.45

Ref: 86-MM3264.00

N-Nitroso-Vortioxetine-D8

Controlled Product

CAS: 508233-74-7, 960203-27-4

Formula: C₁₈H₁₃D₈N₃OS

Color and Shape: Neat

Molecular weight: 335.49

Ref: TR-N991171

Vortioxetine Hydrobromide-D8

Controlled Product

CAS: 508233-74-7, 960203-27-4

Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Formula: C₁₈D₈H₁₄N₂S·BrH

Color and Shape: Neat

Molecular weight: 387.407

Ref: TR-V766002

Vortioxetine

Controlled Product

CAS: 508233-74-7

Applications Vortioxetine can be used in biological study of effectiveness of long term vortioxetine treatment of patients with major depressive disorder.
References Vieta, E., et al.: Eur Neuropsychopharm (2017)

Formula: C₁₈H₂₂N₂S

Color and Shape: Neat

Molecular weight: 298.45

Ref: TR-V760100

1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine

CAS: 508233-74-7

1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine

Formula: C₁₈H₂₂N₂S

Purity: 98%

Molecular weight: 298.45

Ref: IN-DG224799

Vortioxetine

CAS: 508233-74-7

Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.

Formula: C₁₈H₂₂N₂S

Purity: 99.34% - 99.78%

Color and Shape: White Solid

Molecular weight: 298.45

Ref: TM-T2395

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.45

Ref: ST-EA-CP-V36000

Vortioxetine

Controlled Product

CAS: 508233-74-7

Vortioxetine is a serotonin modulator and reuptake inhibitor which appears to be much more potent on serotonin reuptake inhibition and 5-HT3 receptor antagonism than other interactions with the 5-HT receptor family. This drug binds selectively to 5-HT receptors and inhibits the activity of serotonin reuptake transporters on presynaptic neurons, thereby increasing serotonin concentrations in the brain. It is used for the treatment of major depressive disorder (MDD)and has also been shown to be effective against depression-related symptoms such as sleep disturbances, appetite disturbance, and weight change. Vortioxetine has also been demonstrated to suppress glioblastoma in both ex vivo human tissue samples and in mice. This may indicate vortioxetine signalling cascade activation supresses cancer cell division, and could constitute an effective part of a treatment regime for glioblastoma patients.

Formula: C₁₈H₂₂N₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 298.45 g/mol

Ref: 3D-FD58721

Vortioxetine-[d8] 2HBr

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.4

Ref: BE-MD-7725

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.4

Ref: BE-RMCV100000

Vortioxetine in Methanol

CAS: 508233-74-7

Methanol

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.4

Ref: BE-MU-7725YM-1000

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Molecular weight: 298.4

Ref: BE-MU-7725