CAS 51059-44-0

Wogonoside

Description:

Wogonoside, with the CAS number 51059-44-0, is a flavonoid glycoside derived from the plant Scutellaria baicalensis, commonly known as Chinese skullcap. It is characterized by its structure, which consists of a flavone backbone with a glucose moiety attached, contributing to its solubility and biological activity. Wogonoside exhibits a range of pharmacological properties, including anti-inflammatory, antioxidant, and anticancer effects, making it a subject of interest in medicinal chemistry and pharmacology. Its mechanism of action often involves the modulation of various signaling pathways and the inhibition of specific enzymes. Additionally, wogonoside has been studied for its potential neuroprotective effects and its ability to enhance the efficacy of certain chemotherapeutic agents. The compound is typically extracted from plant sources and can be analyzed using techniques such as high-performance liquid chromatography (HPLC) for purity and concentration assessment. Overall, wogonoside represents a promising natural product with significant therapeutic potential.

Formula: C₂₂H₂₀O₁₁

InChI: InChI=1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1

InChI key: InChIKey=LNOHXHDWGCMVCO-NTKSAMNMSA-N

SMILES: O(C)C1=C2C(=C(O)C=C1O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)C(=O)C=C(O2)C4=CC=CC=C4

Synonyms:

• 5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• Beta-D-Glucopyranosiduronic Acid
• Glychionide B
• Oroxindin
• Wogonin 7-O-glucuronide
• Wogonin 7-O-β-<span class="text-smallcaps">D</span>-glucuronide
• Wogonin 7-O-β-<span class="text-smallcaps">D</span>-glucuronopyranoside
• Wogonin 7-glucuronide
• Wogonin 7-β-<span class="text-smallcaps">D</span>-glucuronide
• Wogonoside
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• β-D-Glucopyranosiduronic acid, 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• Wogonin 7-β-D-glucuronide
• 5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl hexopyranosiduronic acid
• 4H-1-benzopyran-4-one, 7-(hexopyranuronosyloxy)-5-hydroxy-8-methoxy-2-phenyl-

Wogonoside

CAS: 51059-44-0

Formula: C₂₂H₂₀O₁₁

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 460.39

Ref: 3B-W0012

Wogonoside

CAS: 51059-44-0

Wogonoside

Formula: C₂₂H₂₀O₁₁

Purity: >97%

Molecular weight: 460.4

Ref: 54-OR1025286

Wogonoside

CAS: 51059-44-0

Wogonoside

Formula: C₂₂H₂₀O₁₁

Purity: ≥98%

Molecular weight: 460.391

Ref: 54-BUP06538

Wogonoside

CAS: 51059-44-0

Formula: C₂₂H₂₀O₁₁

Molecular weight: 460.39

Ref: 7W-GC0670

Wogonoside

CAS: 51059-44-0

Wogonoside has anticoagulant, anti-inflammatory, anti-angiogenic and anticancer effects, it may exert its anti-inflammatory effect via dual inhibition of NF-κB and NLRP3 inflammasome. Wogonoside induced autophagy through the MAPK-mTOR pathway, it inhibited LTB 4 production at the concentration of 100 uM.

Formula: C₂₂H₂₀O₁₁

Purity: 95%~99%

Molecular weight: 460.391

Ref: BP-BP1454

Wogonoside

CAS: 51059-44-0

Wogonoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₂₀O₁₁

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 460.4

Ref: 11-1407S

Wogonoside

CAS: 51059-44-0

Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.

Formula: C₂₂H₂₀O₁₁

Purity: 99.02% - >99.99%

Color and Shape: Solid

Molecular weight: 460.39

Ref: TM-T3318

Wogonoside

CAS: 51059-44-0

(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Formula: C₂₂H₂₀O₁₁

Purity: 98+%

Molecular weight: 460.39

Ref: IN-DG116512

Wogonoside

CAS: 51059-44-0

Natural glycoside

Formula: C₂₂H₂₀O₁₁

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 460.39

Ref: 5G-82684

Wogonoside

CAS: 51059-44-0

Wogonoside is a naturally occurring flavonoid glycoside, which is derived primarily from Scutellaria baicalensis, a traditional Chinese medicinal herb. It functions through its ability to modulate various biochemical pathways, demonstrating significant anti-inflammatory and anticancer properties. Wogonoside exerts its effects by inhibiting key enzymes and signaling pathways involved in inflammation, such as nuclear factor-kappa B (NF-κB), and inducing apoptosis in cancer cells through the activation of caspases and modulation of apoptosis-related proteins.

Formula: C₂₂H₂₀O₁₁

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 460.39 g/mol

Ref: 3D-MW15965

Wogonoside

CAS: 51059-44-0

Formula: C₂₂H₂₀O₁₁

Molecular weight: 460.4

Ref: BE-RMT12090

Wogonoside

CAS: 51059-44-0

Applications Wogonoside is a flavonoid present in extracts from plant Radic scutellariae and provides antioxidant activity.
References Cui, X. et al.: J. Chrom. Sci., 54, 312 (2016);

Formula: C₂₂H₂₀O₁₁

Color and Shape: Neat

Molecular weight: 460.39

Ref: TR-W499360

β-D-GLUCOPYRANOSIDURONIC ACID

CAS: 51059-44-0

Formula: C₂₂H₂₀O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.3876

Ref: IN-DA00DEJI