CAS 51419-59-1

(4-methylphenyl)methanesulfonyl chloride

Description:

(4-Methylphenyl)methanesulfonyl chloride, also known as p-tolylmethanesulfonyl chloride, is an organic compound characterized by the presence of a sulfonyl chloride functional group attached to a methanesulfonyl moiety and a para-methylphenyl group. It appears as a colorless to pale yellow liquid or solid, depending on temperature and purity. This compound is known for its reactivity, particularly in nucleophilic substitution reactions, where it can act as a sulfonylating agent. It is commonly used in organic synthesis for the preparation of sulfonamides and other derivatives. The presence of the sulfonyl chloride group makes it a potent electrophile, allowing it to react with various nucleophiles, including amines and alcohols. Additionally, it is important to handle this compound with care due to its corrosive nature and potential to release toxic gases upon hydrolysis. Proper safety measures, including the use of personal protective equipment and working in a well-ventilated area, are essential when working with this chemical.

Formula: C₈H₉ClO₂S

InChI: InChI=1/C8H9ClO2S/c1-7-2-4-8(5-3-7)6-12(9,10)11/h2-5H,6H2,1H3

SMILES: Cc1ccc(cc1)CS(=O)(=O)Cl

Synonyms:

• P-Tolylmethanesulfonyl Chloride
• 4-Methylbenzylsulfonyl chloride

(4-Methylphenyl)methylsulphonyl chloride

CAS: 51419-59-1

(4-Methylphenyl)methylsulphonyl chloride

Formula: C₈H₉ClO₂S

Purity: >97%

Color and Shape: Solid

Molecular weight: 204.67386

Ref: 54-OR12685

p-Tolylmethanesulfonyl chloride

CAS: 51419-59-1

Formula: C₈H₉ClO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 204.6739

Ref: IN-DA00343V

p-Tolylmethanesulfonyl chloride

CAS: 51419-59-1

p-Tolylmethanesulfonyl chloride

Formula: C₈H₉ClO₂S

Purity: 96%

Molecular weight: 204.67

Ref: IN-DG149539

p-Tolyl-methanesulfonyl chloride

CAS: 51419-59-1

Formula: C₈H₉ClO₂S

Purity: 95%

Color and Shape: Chunks,Crystalline Powder

Molecular weight: 204.67

Ref: 10-F020886

4-Methylbenzylsulfonyl chloride

CAS: 51419-59-1

4-Methylbenzylsulfonyl chloride is a nontoxic chemical compound that inhibits the growth of breast cancer cells. It has been shown to react with and destroy RNA, proteins, and enzymes that are involved in cell division. 4-Methylbenzylsulfonyl chloride also has been shown to have antitumour activity in breast cancer cells. This compound is active against the MDA-MB-231 cell line, which is a human breast cancer cell line derived from metastatic mammary adenocarcinoma. The mechanisms of action of 4-methylbenzylsulfonyl chloride include interference with the synthesis of urokinase, an enzyme that plays an important role in tumour proliferation, as well as inhibition of the cyclooxygenase pathway and other biochemical pathways involved in urokinase production. 4-Methylbenzylsulfonyl chloride may also inhibit angiogenesis by inhibiting trypsin or

Formula: C₈H₉ClO₂S

Purity: Min. 95%

Molecular weight: 204.67 g/mol

Ref: 3D-FM52985