CAS 515-64-0: Sulfisomidine
Description:Sulfisomidine, with the CAS number 515-64-0, is a sulfonamide antibiotic that belongs to the class of compounds known as sulfa drugs. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial cell metabolism. This compound typically appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Sulfisomidine is primarily used in the treatment of bacterial infections, particularly those caused by susceptible strains of bacteria. Its mechanism of action involves competitive inhibition of the enzyme dihydropteroate synthase, which is crucial in the folate synthesis pathway. While effective against a range of gram-positive and some gram-negative bacteria, the use of sulfisomidine has declined due to the emergence of antibiotic resistance and the availability of more effective alternatives. As with other sulfonamides, potential side effects may include allergic reactions, gastrointestinal disturbances, and hematological issues, necessitating careful monitoring during treatment.
Formula:C12H14N4O2S
InChI:InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key:InChIKey=YZMCKZRAOLZXAZ-UHFFFAOYSA-N
SMILES:O=S(=O)(NC1=NC(=NC(=C1)C)C)C2=CC=C(N)C=C2
- Synonyms:
- 2,4-Dimethyl-6-sulfanilamidopyrimidine
- 2,6-Dimethyl-4-sulfanilamidopyrimidine
- 4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide
- 4-Sulfanilamido-2,6-dimethylpyrimidine
- 4-[[(2,6-Dimethylpyrimidin-4-yl)amino]sulfonyl]aniline
- 4-amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide
- 6-(4-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine
- 6-(Sulfanilamido)-2,4-dimethyl-1,3-diazine
- 6-(p-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine
- 6-(p-Aminophenylsulfonamido)-2,4-dimethylpyrimidine
- See more synonyms
- 6-Sulfanilamido-2,4-dimethylpyrimidine
- 6-[(p-Aminobenzenesulfonyl)amino]-2,4-dimethylpyrimidine
- Aristamid
- Aristogyn
- Benzenesulfonamide, 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)-
- Domain
- Domian
- Elcosin
- Elcosine
- Elkosil
- Elkosin
- Elkosine
- Elkozin
- Erycon
- Mefenal
- N1-(2,6-dimethylpyrimidin-4-yl)sulphanilamide
- N<sup>1</sup>-(2,6-Dimethyl-4-pyrimidinyl)sulfanilamide
- Sulfadimetine
- Sulfaisodimerazine
- Sulfamethine
- Sulfanilamide, N<sup>1</sup>-(2,6-dimethyl-4-pyrimidinyl)-
- Sulfasomidin
- Sulfasomidine
- Sulfisomidin
- Sulfisomidine = N1-(2,6-Dimethypyridin-4-yl)sulfanilamide
- Sulphasomidine
- Sulphisomidine
- Sulfanilamide, N1-(2,6-dimethyl-4-pyrimidinyl)-
