CAS 519-02-8

Matrine

Description:

Matrine is an alkaloid derived from the Sophora plant, particularly from Sophora flavescens, and is known for its various biological activities. It is a colorless to pale yellow crystalline solid with a molecular formula of C15H24N2O. Matrine exhibits a range of pharmacological properties, including anti-inflammatory, anti-tumor, and anti-viral effects, making it of interest in medicinal chemistry and pharmacology. Its mechanism of action involves modulation of various signaling pathways, which contributes to its therapeutic potential. Matrine is soluble in organic solvents like ethanol and methanol but has limited solubility in water. Due to its biological activity, it has been studied for potential applications in treating conditions such as cancer and liver diseases. However, further research is needed to fully understand its efficacy and safety profile in clinical settings. As with many natural products, the extraction and purification processes can influence its potency and bioavailability, which are critical factors in its application in medicine.

Formula: C₁₅H₂₄N₂O

InChI: InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1

InChI key: InChIKey=ZSBXGIUJOOQZMP-JLNYLFASSA-N

SMILES: O=C1N2[C@@]([C@@]3([C@@]4([C@](C2)(CCCN4CCC3)[H])[H])[H])(CCC1)[H]

Synonyms:

• (5Beta)-Matridin-15-One
• (5Beta,6Beta,7Beta,11Alpha)-Matridin-15-One
• (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
• 1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)-
• Alkaloids Sophora Flavescen
• Alpha-Matrine
• Bioca
• Matridin-15-One
• Matrine AS
• Matrine-fluensulfone mixt.
• NSC 146051
• NSC 318810
• Vegard
• α-Matrine
• Matrine

Matrine

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 248.37

Ref: 3B-M2120

MATRINE CRS

CAS: 519-02-8

MATRINE CRS

Ref: 41-Y0002013

Matrine

CAS: 519-02-8

Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.

Formula: C₁₅H₂₄N₂O

Purity: 97.16% - >99.99%

Color and Shape: Solid

Molecular weight: 248.36

Ref: TM-T2870

Matrine

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Purity: ≥ 97.0%

Color and Shape: White, off-white or yellow powder

Molecular weight: 248.36

Ref: 7W-GP0925

Matrine

CAS: 519-02-8

Matrine

Purity: ≥95%

Molecular weight: 248.36g/mol

Ref: 54-BUP15754

LC PestiMix 10 10 µg/mL in Acetonitrile

CAS: 119515-38-7, 120-36-5, 120068-36-2, 139542-32-8, 149878-40-0, 158063-66-2, 1689-84-5, 1702-17-6, 1918-00-9, 1918-02-1, 207502-65-6, 33089-74-6, 4710-17-2, 519-02-8, 521-88-0, 534-52-1, 55335-06-3, 58667-63-3, 86-86-2, 87-86-5, 88-85-7, 93-65-2, 94-74-6, 94-75-7, 94-81-5

Color and Shape: Mixture

Ref: 04-A50000810AL

Matrine 100 µg/mL in Acetonitrile

Controlled Product

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Color and Shape: Single Solution

Molecular weight: 248.36

Ref: 04-A14756000AL-100

Matrine

CAS: 519-02-8

Matrine, an alkaloid purified from the chinese herb Sophora flavescens Ait, is well known to possess activities including anti-inflammation, anti-fibrotic and anticancer, it could inhibit cell proliferation and induce apoptosis of SGC-7901 cells in vitro by up-regulating Fas/FasL expression and activating caspase-3 enzyme.

Formula: C₁₅H₂₄N₂O

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 248.37

Ref: BP-BP0928

Matrine

Controlled Product

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Color and Shape: Neat

Molecular weight: 248.36

Ref: 04-C14756000

Matrine

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Molecular weight: 248.37

Ref: 4Z-M-291002

Matrine

CAS: 519-02-8

Natural alkaloid

Formula: C₁₅H₂₄N₂O

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 248.37

Ref: 5G-89730

(+)-Matrine-D₃ (Major)

Controlled Product

CAS: 519-02-8

Formula: C₁₅D₃H₂₁N₂O

Color and Shape: Off White

Molecular weight: 251.38

Ref: TR-M368141

(+)-Matrine

CAS: 519-02-8

Applications (+)-Matrine is an alkaloid compound extracted from the roots of Sophora species which maintain anti-inflammatory, anti-cancer and a host of other positive pharmacological effects. Apoptotic agent.
References Xie, B. et al.: Mol. Med. Rep., 9, 2547 (2014); Liu, Y. et al.: Tumor Biol., 35, 5111 (2014);

Formula: C₁₅H₂₄N₂O

Color and Shape: Off-White

Molecular weight: 248.36

Ref: TR-M197870

Matrine

CAS: 519-02-8

Matrine is an alkaloid found in plants of the Sophora genus. The compound is an antioxidant with anti-tumoral properties and has neuroprotective effects in rodent models for Parkinson’s disease. It inhibits inflammatory responses and was shown to attenuates collagen-induced arthritis in mice. Moreover, matrine can attenuate cardiac fibrosis and hepatitis B-induced liver damage. The compound can also agonise opioid receptors and has anti-nociceptive properties.

Formula: C₁₅H₂₄N₂O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 248.36 g/mol

Ref: 3D-FM65961

Matrine

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Purity: 95.0%

Molecular weight: 248.37

Ref: 10-F464368

(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

CAS: 519-02-8

Formula: C₁₅H₂₄N₂O

Color and Shape: Solid

Molecular weight: 248.3639

Ref: IN-DA0037PX