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CAS 51940-44-4

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pipemidic acid

Description:
Pipemidic acid is a synthetic antimicrobial agent belonging to the class of quinolone carboxylic acids. It is primarily used as an antibiotic for the treatment of urinary tract infections. The compound exhibits broad-spectrum activity against various Gram-negative and some Gram-positive bacteria, functioning by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for DNA replication and transcription. Pipemidic acid is characterized by its relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. The substance is typically administered orally and is known for its favorable safety profile, although it may cause side effects such as gastrointestinal disturbances or allergic reactions in some individuals. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. As with many antibiotics, the emergence of resistance is a concern, necessitating careful use and monitoring in clinical settings. Overall, pipemidic acid remains a valuable option in the treatment of specific bacterial infections, particularly in the context of urinary tract health.
Formula:C6H11NO2
InChI:InChI=1/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22)
InChI key:InChIKey=JOHZPMXAZQZXHR-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CN=C(N2)N3CCNCC3
Synonyms:
  • 1489Rb
  • 8-Ethyl-2-(piperazin-1-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
  • 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid
  • 8-Ethyl-5-Oxo-2-(Piperazin-1-Yl)-5,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylic Acid
  • Deblaston
  • Dolcol
  • Filtrax
  • Memento 400
  • Palin
  • Pi-Coli
  • See more synonyms
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