CAS 524-12-9
:Wedelolactone
Description:
Wedelolactone is a naturally occurring compound classified as a coumarin derivative, primarily extracted from various plants, including those in the genus *Wedelia*. It is characterized by its aromatic structure, which includes a lactone functional group, contributing to its distinctive chemical properties. The compound exhibits a range of biological activities, including anti-inflammatory, antioxidant, and potential anticancer effects, making it of interest in pharmacological research. Wedelolactone is soluble in organic solvents but has limited solubility in water, which influences its bioavailability and application in medicinal chemistry. Its molecular formula is C10H10O3, and it has a relatively low molecular weight. The compound's structure allows it to interact with various biological targets, and ongoing studies continue to explore its therapeutic potential. Additionally, due to its natural origin, wedelolactone is often investigated for its role in traditional medicine and its possible applications in modern therapeutic contexts.
Formula:C16H10O7
InChI:InChI=1/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
InChI key:InChIKey=XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES:O=C1C2=C(C=3C(O1)=CC(OC)=CC3O)OC=4C2=CC(O)=C(O)C4
Synonyms:- 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
- 1,8,9-Trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one
- 1,8,9-trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one
- 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-
- 7-Methoxy-5,11,12-Trihydroxycoumestan
- Wedelolactone
- Wedelia lactone
- Wedelolactone, ≥98%(HPLC)
- 5,11,12-Trihydroxy-7-MethoxycouMestan
- IKK Inhibitor II, Wedelolactone
- Wedelolactone CRS
- Wedelolactone, 98%, from Wedelia chinensis (Osbeck.) Merr.
- 1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one
- See more synonyms
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Found 13 products.
Wedelolactone
CAS:Wedelolactone analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C16H10O7Purity:(HPLC) ≥99%Color and Shape:PowderMolecular weight:314.251,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
CAS:Formula:C16H10O7Purity:98%Color and Shape:SolidMolecular weight:314.2464Wedelolactone
CAS:Wedelolactone is a potent Î2-arrestin-biased G protein-coupled receptor-35 (GPR35) agonist, GPR35 has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium. Wedelolactone has anti-inflammatory, growth inhibitory, anti-cancer, anti-fibrotic, and pro-apoptotic effects. Wedelolactone stimulates ER genomic and non-genomic signalling pathways; it can significantly inhibit the activation of LX-2 cells, the underlying mechanisms of which included inducing Bcl-2 family involved apoptosis, up-regulating phosphorylated status of ERK and JNK expressions, and inhibiting NF-κB mediated activity.Formula:C16H10O7Purity:95%~99%Molecular weight:314.249Wedelolactone
CAS:Formula:C16H10O7Purity:>98.0%(HPLC)Color and Shape:White to Dark green powder to crystalMolecular weight:314.25Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Wedelolactone
CAS:LactoneFormula:C16H10O7Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:314.25Wedelolactone
CAS:<p>Wedelolactone is a naturally occurring bioactive compound, classified as a coumestan, which is derived from the plant Eclipta alba, commonly referred to as false daisy. This polyphenolic compound exerts its effects through various modes of action, including inhibition of 5-lipoxygenase and modulation of NF-κB signaling pathways. The inhibition of these pathways suggests its potential role in the regulation of inflammation and cell proliferation.</p>Formula:C16H10O7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:314.25 g/molWedelolactone
CAS:<p>M06041 - Wedelolactone</p>Formula:C16H10O7Purity:98%Color and Shape:SolidMolecular weight:314.249
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