CAS 53152-21-9

Buprenorphine hydrochloride

Description:

Buprenorphine hydrochloride is a semi-synthetic opioid used primarily in the treatment of opioid addiction and pain management. It is classified as a partial agonist at the mu-opioid receptor, which means it activates the receptor but to a lesser degree than full agonists like morphine. This property helps reduce withdrawal symptoms and cravings in individuals with opioid dependence while minimizing the risk of overdose. Buprenorphine is also known for its ceiling effect, where increasing doses do not lead to a proportional increase in effects, making it safer than many other opioids. The hydrochloride salt form enhances its solubility and stability, facilitating its administration via various routes, including sublingual and transdermal. Buprenorphine has a long half-life, allowing for less frequent dosing, which can improve patient compliance. Common side effects may include nausea, constipation, and sedation, and it is important to monitor for potential interactions with other medications. Due to its potential for abuse, buprenorphine is classified as a controlled substance in many jurisdictions.

Formula:C₂₉H₄₁NO₄·ClH

InChI:InChI=1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1

InChI key:InChIKey=UAIXRPCCYXNJMQ-RZIPZOSSSA-N

SMILES:O(C)[C@@]12[C@]3([C@]45[C@@]([C@](N(CC6CC6)CC4)(CC7=C5C(O3)=C(O)C=C7)[H])(C[C@@]1([C@](C(C)(C)C)(C)O)[H])CC2)[H].Cl

Synonyms:

(5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol hydrochloride
(5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
21-Cyclopropyl-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine hydrochloride
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, hydrochloride, (5alpha,7alpha(S))-
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride (1:1), (αS,5α,7α)-
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride, (αS,5α,7α)-
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride, [5α,7α(S)]-
Buprederm
Buprenex
Buprenorphine HCl
Buprenorphine hydrochloride [USAN:JAN]
Buprex
Cl 112,302
DEA No. 9064
Finibron
Lepetan
M 6029
Mr 56
Nih 8805
Rx 6029-M
Sixmo
Subutex
Temgesic
Um 952
Unii-56W8Mw3En1
Vetergesic
Buprenorphine hydrochloride
See more synonyms

Purity (%)

100

Found 9 products.

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Buprenorphine.HCl, 1mg/ml in Methanol (as free base)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Color and Shape:Single Solution
Ref: LP-BUP-399-HC-1LM
1ml
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Buprenorphine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Formula:C₂₉H₄₁NO₄·ClH
Color and Shape:Neat
Molecular weight:504.101
Ref: 86-MM1237.00
250mg
To inquire
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Buprenorphine.HCl
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Color and Shape:Neat
Ref: LP-BUP-399-HC
10mg
To inquire
50mg
To inquire
100mg
To inquire
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Buprenorphine-d4 Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Applications Buprenorphine-d4 Hydrochloride, is the labeled analogue of Buprenorphine (B689570), an Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),
Formula:C₂₉D₄H₃₇NO₄·ClH
Color and Shape:Neat
Molecular weight:508.13
Ref: TR-B689573
1mg
428.00€
VAT not included
10mg
2,874.00€
VAT not included
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Buprenorphine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Applications Controlled substance (narcotic). Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),
Formula:C₂₉H₄₁NO₄·ClH
Color and Shape:Neat
Molecular weight:504.101
Ref: TR-B689570
10mg
129.00€
VAT not included
25mg
179.00€
VAT not included
50mg
269.00€
VAT not included
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Buprenorphine hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Please enquire for more information about Buprenorphine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C₂₉H₄₂ClNO₄
Molecular weight:504.1 g/mol
Ref: 3D-FB19361
10g
10,702.00€
VAT not included
100g
21,403.00€
VAT not included
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BUPRENORPHINE HYDROCHLORIDE CRS - * PSY
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
BUPRENORPHINE HYDROCHLORIDE CRS - * PSY
Formula:C₂₉H₄₂ClNO₄
Color and Shape:Crystalline Powder. White. Powder.
Molecular weight:504.1011
Ref: 41-Y0001109
10mg
132.00€
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Buprenorphine hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Buprenorphine hydrochloride
Formula:C₂₉H₄₁NO₄HCl
Purity:99.8%
Color and Shape:White
Molecular weight:503.28024
Ref: 47-1062
100mg
242.00€
VAT not included
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Buprenorphine Hydrochloride CIII
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 53152-21-9
Concentrates of poppy straw; buprenorphine (inn) codein
Formula:C₂₉H₄₁NO₄·ClH
Color and Shape:White Powder
Molecular weight:503.28024
Ref: 45-1078700