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CAS 549-18-8

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Amitriptyline hydrochloride

Description:
Amitriptyline hydrochloride is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. It is characterized by its chemical formula C20H23N·HCl, indicating the presence of a hydrochloride salt. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Amitriptyline acts by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing mood and alleviating pain. Its pharmacological effects can lead to side effects, including sedation, dry mouth, and weight gain, among others. The drug is typically administered orally and is known for its relatively long half-life, which allows for once-daily dosing in many cases. Due to its potential for overdose and interactions with other medications, careful monitoring is essential during treatment. Amitriptyline hydrochloride is classified as a prescription medication and should be used under the guidance of a healthcare professional.
Formula:C20H23N·ClH
InChI:InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
InChI key:InChIKey=KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
  • 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
  • 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Δ<sup>5</sup>,γ-propylamine hydrochloride
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
  • 5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene hydrochloride
  • 5H-Dibenzo[a,d]cycloheptene-Δ<sup>5,γ</sup>-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride
  • Adepril
  • Amicen
  • Amil 25
  • Amilent
  • See more synonyms
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