CAS 553-21-9

(+)-Costunolide

Formula: C₁₅H₂₀O₂

InChI: InChI=1/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5u,11-9+/t13-,14+/m0/s1

InChI key: InChIKey=HRYLQFBHBWLLLL-AHNJNIBGSA-N

SMILES: C=C1[C@]2([C@](OC1=O)(/C=C(\C)/CC/C=C(\C)/CC2)[H])[H]

Synonyms:

• (3aS,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one
• (3aS,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one
• (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one
• (3aS,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one
• Costunolid
• Costus lactone
• Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, (3aS,6E,10E,11aR)-
• Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, [3aS-(3aR*,6E,10E,11aS*)]-
• Germacra-1(10),4,11(13)-trien-12-oic acid, 6α-hydroxy-, γ-lactone, (E,E)-
• NSC 106404
• Saussurea costus
• Saussurea lappa

Costunolide

CAS: 553-21-9

Formula: C₁₅H₂₀O₂

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 232.32

Ref: 3B-C2921

COSTUNOLIDE CRS

CAS: 553-21-9

COSTUNOLIDE CRS

Formula: C₁₅H₂₀O₂

Molecular weight: 232.3181

Ref: 41-Y0001307

Cyclodeca[b]furan-2(3H)-one,3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-,(3aS,6E,10E,11aR)-

CAS: 553-21-9

Formula: C₁₅H₂₀O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.3181

Ref: IN-DA00I9V6

(3aS,6E,10E,11aR)-6,10-Dimethyl-3-Methylene-3A,4,5,8,9,11A-Hexahydrocyclodeca[B]Furan-2(3H)-One

CAS: 553-21-9

(3aS,6E,10E,11aR)-6,10-Dimethyl-3-Methylene-3A,4,5,8,9,11A-Hexahydrocyclodeca[B]Furan-2(3H)-One

Formula: C₁₅H₂₀O₂

Purity: 99%

Molecular weight: 232.32

Ref: 54-OR1008103

Costunolide

CAS: 553-21-9

Costunolide

Formula: C₁₅H₂₀O₂

Purity: ≥90%

Molecular weight: 232.32

Ref: 54-BUP13315

Costunolide

CAS: 553-21-9

Costunolide, a sesquiterpene lactone isolated from the root of Saussurea lappa Clarke, has a variety of biological activities, including anti-carcinogenic and anti-fungal activities,

Formula: C₁₅H₂₀O₂

Purity: 95%~99%

Color and Shape: Cryst.

Molecular weight: 232.323

Ref: BP-BP0401

Costunolide

CAS: 553-21-9

Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.

Formula: C₁₅H₂₀O₂

Purity: 97.19% - >99.99%

Color and Shape: Solid

Molecular weight: 232.32

Ref: TM-T2902

Costunolide

CAS: 553-21-9

Formula: C₁₅H₂₀O₂

Purity: ≥ 98.0%

Color and Shape: White to beige crystalline powder

Molecular weight: 232.323

Ref: 7W-GX8820

Costunolide

CAS: 553-21-9

Lactone

Formula: C₁₅H₂₀O₂

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 232.32

Ref: 5G-89611

(+)-Costunolide

Controlled Product

CAS: 553-21-9

Applications (+)-Costunolide is an inhibitor of osteoclast differentiation, acting as an anti-inflammatory and anti-oxidant agent. It is a sesquiterpene lactone which mediates apoptosis.
References Cheon, Y. et al.: Phytother. Res., 28, 586 (2014); Butturini, E. et al.: Eur. J. Pharm., 730, 107 (2014);

Formula: C₁₅H₂₀O₂

Color and Shape: Neat

Molecular weight: 232.32

Ref: TR-C697550

Costus lactone

CAS: 553-21-9

Costus lactone is a naturally occurring sesquiterpene lactone, which is derived from the roots of the plant Saussurea lappa, commonly known as costus. This sesquiterpene is a secondary metabolite that exhibits various bioactive properties. Costus lactone achieves its effects primarily through interactions with microbial cell membranes and can inhibit growth and replication by disrupting cellular processes crucial to microbial survival.

Formula: C₁₅H₂₀O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 232.32 g/mol

Ref: 3D-FC65612