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CAS 56238-63-2

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Cefuroxime sodium

Description:
Cefuroxime sodium is a broad-spectrum cephalosporin antibiotic, primarily used to treat various bacterial infections. It is a sodium salt of cefuroxime, which is a second-generation cephalosporin. This compound exhibits a beta-lactam structure, which is essential for its antibacterial activity, as it interferes with bacterial cell wall synthesis. Cefuroxime sodium is typically administered via injection and is effective against a range of Gram-positive and Gram-negative bacteria. It is often used in the treatment of respiratory tract infections, skin infections, and urinary tract infections. The substance is soluble in water, which facilitates its use in injectable formulations. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, hematological effects. As with other antibiotics, it is crucial to use cefuroxime sodium judiciously to prevent the development of antibiotic resistance. Proper storage conditions are necessary to maintain its stability and efficacy, typically requiring protection from light and moisture.
Formula:C16H16N4NaO8S
InChI:InChI=1/C16H16N4O8S.Na/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20;/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24);/q;+1/p-1/b19-9-;/t10-,14-;/m1./s1
InChI key:InChIKey=BAJSKIYRJKPEIM-JTBFTWTJSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CC=CO3)=O)C2=O)(SCC1COC(N)=O)[H].[Na]
Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, sodium salt (1:1), (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]-
  • 640/359
  • Anaptivan
  • Biociclin
  • Biofurex
  • Bioxima
  • Cefamar
  • Cefoprim
  • See more synonyms
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