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CAS 57-68-1

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Sulfamethazine

Description:
Sulfamethazine is a sulfonamide antibiotic that belongs to the class of sulfa drugs, which are synthetic antimicrobial agents. It is primarily used in veterinary medicine for the treatment of bacterial infections in livestock and poultry. The chemical structure of sulfamethazine features a sulfonamide group, which is responsible for its antibacterial activity, and it is characterized by its ability to inhibit bacterial growth by interfering with folic acid synthesis. This compound is typically administered orally and is known for its relatively low toxicity in animals. Sulfamethazine is soluble in water and exhibits stability under various conditions, although it can degrade in the presence of strong acids or bases. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, with a half-life that can vary depending on the species and dosage. While effective against a range of pathogens, the use of sulfamethazine has raised concerns regarding antibiotic resistance and potential residues in food products, leading to regulatory scrutiny in some regions.
Formula:C12H14N4O2S
InChI:InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key:InChIKey=ASWVTGNCAZCNNR-UHFFFAOYSA-N
SMILES:S(NC=1N=C(C)C=C(C)N1)(=O)(=O)C2=CC=C(N)C=C2
Synonyms:
  • (p-Aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin
  • 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine
  • 2-(4-Aminobenzenesulfonylamino)-4,6-dimethylpyrimidine
  • 2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine
  • 2-Sulfanilamido-4,6-dimethylpyrimidine
  • 4,6-Dimethyl-2-sulfanilamidopyrimidine
  • 4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide
  • 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
  • 4-Amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
  • A 502
  • See more synonyms
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