CAS 59-87-0

Nitrofurazone

Description:

Nitrofurazone is an organic compound classified as a nitrofuran derivative, primarily known for its antimicrobial properties. It appears as a yellow to orange crystalline powder and is soluble in organic solvents but has limited solubility in water. The chemical formula of Nitrofurazone is C₇H₆N₄O₄, and it features a nitro group (-NO₂) attached to a furan ring, which contributes to its biological activity. Nitrofurazone is commonly used in veterinary medicine for the treatment of bacterial infections and is also employed in topical formulations for wound healing due to its ability to inhibit bacterial growth. Its mechanism of action involves the disruption of bacterial DNA and protein synthesis. While effective, Nitrofurazone can cause side effects, including skin irritation and allergic reactions in some individuals. Due to its potential toxicity and the development of resistance, its use is regulated in many countries, and it is important to follow guidelines for safe application.

Formula: C₆H₆N₄O₄

InChI: InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)

InChI key: InChIKey=IAIWVQXQOWNYOU-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1OC(C=NNC(N)=O)=CC1

Synonyms:

• (5-Nitro-2-furfurylidenamino)urea
• 1-(5-Nitro-2-furfurylidene)semicarbazide
• 2-Furaldehyde, 5-nitro-, semicarbazone
• 2-Furancarboxaldehyde, 5-nitro-, semicarbazone
• 2-Nitrofuran
• 2-[(5-Nitro-2-Furanyl)Methylene]-Hydrazinecarboxamide
• 5-Nitro-2-Furaldehyd-Semicarbazon
• 5-Nitro-2-furaldehyde semicarbazone
• 5-Nitro-2-furfural semicarbazone
• 5-Nitro-2-furfuraldehyde semicarbazone
• 5-Nitrofuran-2-Carbaldehyde Semicarbazone
• 5-Nitrofurazone
• 5-Nitrofurfural semicarbazone
• Aldomycin
• Alfucin
• Amifur
• Babrocid
• Chemofuran
• Coxistat
• Fura-Septin
• FuraZin
• Furacilin
• Furacilinum
• Furacin
• Furacin Ointment
• Furacine
• Furacinetten
• Furacoccid
• Furacycline
• Furalcyn
• Furaldon
• Furaplast
• Furaseen
• Furaskin
• Furaziline
• Furazol W
• Furesol
• Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-
• Mammex
• Mastofuran
• Monafuracin
• NFS
• Nefco
• Nfz mix
• Nifucin
• Nifuzon
• Nitrofuraldehyde semicarbazone
• Nitrofuran
• Nitrofuran (bactericide)
• Nitrofurazone
• Nitrophtharazone
• Nitrozone
• Nsc 1602
• Nsc 2100
• Nsc 44009
• Otofural
• Semioxamazide, 1-(5-nitrofurfurylidene)-
• Topifuran
• Vabrocid
• Veterinary nitrofurazone

Nitrofurazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Purity: >98.0%(E)(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 198.14

Ref: 3B-N0200

5-Nitro-2-furaldehyde semicarbazone, 98+%

CAS: 59-87-0

Bactericidal compound used as an antibiotic This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as

Formula: C₆H₆N₄O₄

Purity: 98+%

Color and Shape: Yellow, Powder

Molecular weight: 198.14

Ref: 02-A18593

NITROFURAL CRS

CAS: 59-87-0

NITROFURAL CRS

Color and Shape: Modified

Ref: 41-N0950000

NITROFURAL FOR PEAK IDENTIFICATION A CRS

CAS: 59-87-0

NITROFURAL FOR PEAK IDENTIFICATION A CRS

Color and Shape: Modified

Ref: 41-Y0002295

Nitrofurazone

CAS: 59-87-0

Compounds containing an unfused furan ring, whether or not hydrogenated, in the structure, nesoi

Formula: C₆H₆N₄O₄

Color and Shape: Yellow Powder

Molecular weight: 198.14 g/mol

Ref: 45-1465004

2-[(5-Nitro-2-furanyl)methylene]-hydrazinecarboxamide

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Purity: %

Color and Shape: Solid

Molecular weight: 198.1362

Ref: IN-DA0037I8

5-Nitro-2-furaldehyde semicarbazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Purity: ≥ 98.0%

Color and Shape: Yellow powder

Molecular weight: 198.14

Ref: 7W-GK3255

Nitrofurazone

CAS: 59-87-0

Nitrofurazone

Purity: ≥98%

Molecular weight: 198.14g/mol

Ref: 54-BUP19366

Nitrofurazone (Nitrofural)

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Color and Shape: Yellow Solid

Molecular weight: 198.14

Ref: 4Z-N-345

Nitrofural

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Color and Shape: Neat

Molecular weight: 198.14

Ref: 86-MM0943.00

Nitrofurazone (Standard)

CAS: 59-87-0

Nitrofurazone (Standard) is the standard substance of Nitrofurazone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrofurazone (Nitrofural; Furacilin) is an orally active nitroaromatic broad-spectrum antibiotic with activity against both Gram-positive and Gram-negative bacteria. It is commonly used for establishing breast cancer models.

Formula: C₆H₆N₄O₄

Molecular weight: 198.14

Ref: TM-TMSM-1743

Nitrofurazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Color and Shape: Neat

Molecular weight: 198.14

Ref: 04-C15571000

PharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol

Controlled Product

CAS: 14885-29-1, 16773-42-5, 19387-91-8, 35175-14-5, 42116-76-7, 443-48-1, 4812-40-2, 551-92-8, 59-87-0, 67-45-8, 70028-95-4, 7681-76-7, 936-05-0

Color and Shape: Mixture

Ref: 04-A30000037ME

Nitrofurazone

CAS: 59-87-0

Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.

Formula: C₆H₆N₄O₄

Purity: 99.87%

Color and Shape: Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)

Molecular weight: 198.14

Ref: TM-T0897

Nitrofurazone

CAS: 59-87-0

Applications Anti-infective (topical). Antimicrobial.Environmental contaminants; Food contaminants; Heat processing contaminants
References Morris, et al.: Cancer Res., 29, 2145 (1969), Sanderson, H., et al.: Toxicol. Lett., 144, 383 (2003),

Formula: C₆H₆N₄O₄

Color and Shape: Neat

Molecular weight: 198.14

Ref: TR-N493880

Nitrofurazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Molecular weight: 198.14

Ref: ST-EA-CP-N12017

Nitrofurazone

CAS: 59-87-0

Formula: C₆H₆N₄O₄

Purity: 97%

Molecular weight: 198.138

Ref: 10-F544119

Nitrofurazone

CAS: 59-87-0

Nitrofurazone is a synthetic antimicrobial agent that has been shown to be effective against a wide range of bacteria, fungi, and viruses. This drug has been studied using electrochemical impedance spectroscopy (EIS) on cells from rat brain tumors. The EIS study yielded the most promising results when used in combination with malignant brain tumor cells. It was also found that nitrofurazone is not toxic to wild-type strains of Escherichia coli and Saccharomyces cerevisiae, but is toxic to resistant mutants of these organisms. Nitrofurazone may react with nitrite ions in solution to form nitrosating agents that can result in the formation of DNA or protein adducts which can lead to cell death.
Nitrofurazone was tested for its toxicity on human serum at different concentrations and it was found that this drug does not have significant toxicity on human serum.

Formula: C₆H₆N₄O₄

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 198.14 g/mol

Ref: 3D-FN26308

Nitrofural

CAS: 59-87-0

Color and Shape: Neat

Ref: 61-FOR0943.00