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CAS 59277-89-3

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Acyclovir

Description:
Acyclovir is an antiviral medication primarily used to treat infections caused by certain types of viruses, particularly herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its chemical formula is C8H10N5O3, and it is classified as a nucleoside analog. Acyclovir works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral tablets, topical creams, and intravenous solutions. Acyclovir has a relatively low toxicity profile, but side effects can include nausea, diarrhea, and, in rare cases, renal toxicity, particularly with rapid intravenous administration. It is important to note that while acyclovir can effectively manage symptoms and reduce the duration of outbreaks, it does not cure herpes infections. The drug is often prescribed for both initial and recurrent episodes of herpes infections, as well as for prophylactic use in immunocompromised patients.
Formula:C8H11N5O3
InChI:InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key:InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N
SMILES:C(OCCO)N1C2=C(N=C1)C(=O)N=C(N)N2
Synonyms:
  • 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
  • 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one
  • 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one
  • 2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one
  • 2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
  • 2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one
  • 2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-
  • 9-(2-Hydroxyethoxymethyl)guanine
  • 9-[(2-Hydroxyethoxy)methyl]guanine
  • See more synonyms
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