CAS 59338-87-3: Alizapride
Description:Alizapride is a chemical compound classified as a substituted benzamide and is primarily known for its use as an antiemetic and gastroprokinetic agent. It acts as a dopamine receptor antagonist, particularly at the D2 receptor, which contributes to its therapeutic effects in managing nausea and vomiting. Alizapride exhibits a moderate affinity for serotonin receptors as well, which may play a role in its pharmacological profile. The compound is typically administered orally and is characterized by its ability to enhance gastrointestinal motility, making it useful in treating conditions like functional dyspepsia. In terms of its chemical structure, Alizapride features a benzamide core, which is common among many drugs in this class. Its safety and efficacy profile has been evaluated in various clinical settings, although it may be associated with side effects typical of dopamine antagonists, such as sedation or extrapyramidal symptoms. Overall, Alizapride represents a valuable option in the management of gastrointestinal disorders, although its use may vary by region due to regulatory approvals.
Formula:C16H22ClN5O2
InChI:InChI=1/C16H21N5O2.ClH/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2;/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20);1H
- Synonyms:
- Alizapride Hydrochloride
- 6-Methoxy-N-[(1-Prop-2-Enylpyrrolidin-2-Yl)Methyl]-2H-Benzotriazole-5-Carboxamide Hydrochloride
- 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-benzotriazole-5-carboxamide
- 6-methoxy-N-[(1-prop-2-en-1-ylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide hydrochloride
![1H-Benzotriazole-5-carboxamide,6-methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-, monohydrochlo…](https://static.cymitquimica.com/products/IN/thumb/DA00IAJN.jpg)
![N-((1-Allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochloride](https://static.cymitquimica.com/products/10/thumb/F241524.jpg)
