CAS 59338-87-3

Alizapride

Description:

Alizapride is a chemical compound classified as a substituted benzamide and is primarily known for its use as an antiemetic and gastroprokinetic agent. It acts as a dopamine receptor antagonist, particularly at the D2 receptor, which contributes to its therapeutic effects in managing nausea and vomiting. Alizapride exhibits a moderate affinity for serotonin receptors as well, which may play a role in its pharmacological profile. The compound is typically administered orally and is characterized by its ability to enhance gastrointestinal motility, making it useful in treating conditions like functional dyspepsia. In terms of its chemical structure, Alizapride features a benzamide core, which is common among many drugs in this class. Its safety and efficacy profile has been evaluated in various clinical settings, although it may be associated with side effects typical of dopamine antagonists, such as sedation or extrapyramidal symptoms. Overall, Alizapride represents a valuable option in the management of gastrointestinal disorders, although its use may vary by region due to regulatory approvals.

Formula: C₁₆H₂₂ClN₅O₂

InChI: InChI=1/C16H21N5O2.ClH/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2;/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20);1H

SMILES: C=CCN1CCCC1CN=C(c1cc2c(cc1OC)nn[nH]2)O.Cl

Synonyms:

• Alizapride Hydrochloride
• 6-Methoxy-N-[(1-Prop-2-Enylpyrrolidin-2-Yl)Methyl]-2H-Benzotriazole-5-Carboxamide Hydrochloride
• 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-benzotriazole-5-carboxamide
• 6-methoxy-N-[(1-prop-2-en-1-ylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide hydrochloride
• N-((1-Allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochl
• -6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochloride
• 6-Methoxy-N-{[(2S)-1-(prop-2-en-1-yl)pyrrolidin-2-yl]Methyl}-2H-1,2,3-benzotriazole-5-carboxaMide
• 1H-Benzotriazole-5-carboxamide,6-methoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-, hydrochloride (1:1)
• N-((1-Allylpyrrolidin-2-yl)Methyl)-6-Methoxy-1H-benzo[d][1,2,3]triazole-5-carboxaMide hydrochloride
• Alizapride hydrochloride USP/EP/BP
• 1H-Benzotriazole-5-carboxamide,6-methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-, monohydrochloride
• N-((1-Allylpyrrolidin-2-yl)
• Alizapride HCl
• 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-1H-1,2,3-benzotriazole-5-carboxamide hydrochloride

1H-Benzotriazole-5-carboxamide,6-methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-, monohydrochloride

CAS: 59338-87-3

Formula: C₁₆H₂₂ClN₅O₂

Purity: %

Color and Shape: Solid

Molecular weight: 351.8312

Ref: IN-DA00IAJN

Alizapride hydrochloride

CAS: 59338-87-3

Alizapride hydrochloride

Purity: ≥98%

Molecular weight: 351.83g/mol

Ref: 54-BUP15816

Alizapride HCl

CAS: 59338-87-3

Formula: C₁₆H₂₁N₅O₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 315.38 36.46

Ref: 4Z-A-672

Alizapride hydrochloride

CAS: 59338-87-3

Alizapride hydrochloride

Purity: 99%

Molecular weight: 351.83g/mol

Ref: 54-OR1027435

Alizapride-13C-d3 HCl

CAS: 59338-87-3

Formula: C₁₅₁₃CH₁₈D₃N₅O₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 319.39 36.46

Ref: 4Z-A-671

Alizapride hydrochloride

CAS: 59338-87-3

Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.

Formula: C₁₆H₂₁N₅O₂·HCl

Purity: 99.35% - 99.48%

Color and Shape: Coa

Molecular weight: 351.83

Ref: TM-T2574

Alizapride Hydrochloride

CAS: 59338-87-3

Applications Alizapride is a dopamine antagonist with prokinetic and antiemetic effects. Alizapride is used in the treatment of post-operative nausea and vomitting.
References Bleiberg, H. et al.: Cancer Chemother. Pharmacol., 22, 316 (1988);

Formula: C₁₆H₂₁N₅O₂·ClH

Color and Shape: Neat

Molecular weight: 351.83

Ref: TR-A537000

Alizapride hydrochloride

CAS: 59338-87-3

Dopamine (D2) receptor antagonist

Formula: C₁₆H₂₂ClN₅O₂

Purity: Min. 95%

Molecular weight: 351.83 g/mol

Ref: 3D-FA150825