CAS 61-75-6
:bretylium tosylate
Description:
Bretylium tosylate is a quaternary ammonium compound primarily used as an antiarrhythmic agent in medical applications. It is characterized by its ability to block adrenergic receptors, which helps in the management of certain types of cardiac arrhythmias. The compound is typically presented as a white to off-white crystalline powder and is soluble in water and alcohol, making it suitable for intravenous administration. Bretylium tosylate acts by inhibiting the release of norepinephrine from sympathetic nerve endings, leading to a decrease in heart rate and myocardial contractility. Its pharmacological effects are particularly beneficial in emergency situations, such as ventricular fibrillation or tachycardia. However, it may also cause side effects, including hypotension and gastrointestinal disturbances. Due to its specific action on the cardiovascular system, bretylium tosylate is often used in conjunction with other antiarrhythmic medications to enhance therapeutic efficacy. As with all medications, its use should be carefully monitored by healthcare professionals to mitigate potential adverse effects.
Formula:C11H17BrN·C7H7O3S
InChI:InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
InChI key:InChIKey=KVWNWTZZBKCOPM-UHFFFAOYSA-M
SMILES:S(=O)(=O)([O-])C1=CC=C(C)C=C1.C([N+](CC)(C)C)C1=C(Br)C=CC=C1
Synonyms:- (2-Bromophenyl)Methyl-Ethyl-Dimethyl-Ammonium
- (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate
- 2-Bromobenzylethyldimethylammonium Toluene-4-Sulphonate
- 4-Methylbenzenesulfonic Acid
- Ammonium, (o-bromobenzyl)ethyldimethyl-, p-toluenesulfonate
- Asl 603
- Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, 4-methylbenzenesulfonate (1:1)
- Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1)
- Bretylan
- Bretylate
- Bretylium Tosilate
- Bretylium p-toluenesulfonate
- Bretylol
- Darenthin
- N-(2-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate
- N-(4-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate
- N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium tosylate
- NSC 62164
- Ornid
- See more synonyms
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Found 10 products.
Bretylium Tosylate
CAS:Quaternary ammonium salts and hydroxides, whether or not chemically defined, nesoiFormula:C18H24BrNO3SColor and Shape:White PowderMolecular weight:413.06603Bretylium Tosylate
CAS:Formula:C18H24BrNO3SPurity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:414.36Bretylium tosylate
CAS:<p>Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.</p>Formula:C18H24BrNO3SPurity:>99.99%Color and Shape:SolidMolecular weight:414.36Bretylium tosylate
CAS:<p>Inhibitor of sodium/potassium ATP-ase; anti-arrhythmic</p>Formula:C18H24BrNO3SPurity:Min. 95%Color and Shape:PowderMolecular weight:414.36 g/molBretylium Tosylate
CAS:Controlled Product<p>Applications Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase.<br>References Kuntzman, R., et al.: Clin. Pharmacol. Ther., 11, 829 (1970), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Carter, J.E., et al.: Anal. Profiles Drug Subs., 9, 71 (1980),<br></p>Formula:C11H17BrN·C7H7O3SColor and Shape:NeatMolecular weight:414.36Bretylium tosilate
CAS:Bretylium tosilateFormula:C18H24BrNO3SPurity:97.3%Color and Shape:White To Off-WhiteMolecular weight:413.06603
