CAS 61477-96-1

Piperacillin

Description:

Piperacillin is a semisynthetic penicillin antibiotic that is primarily used to treat a variety of bacterial infections. It is effective against a broad spectrum of gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa. Piperacillin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection, as it is not well absorbed when taken orally. Its chemical structure includes a beta-lactam ring, which is characteristic of penicillins, and a side chain that enhances its activity against certain resistant bacteria. Piperacillin is often combined with a beta-lactamase inhibitor, such as tazobactam, to extend its efficacy against beta-lactamase-producing organisms. Common side effects may include allergic reactions, gastrointestinal disturbances, and potential impacts on renal function. Due to its broad-spectrum activity, piperacillin is frequently utilized in hospital settings for serious infections, particularly in immunocompromised patients.

Formula: C₂₃H₂₇N₅O₇S

InChI: InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1

InChI key: InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N

SMILES: N(C([C@H](NC(=O)N1C(=O)C(=O)N(CC)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Synonyms:

• (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-
• Pipracil
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsaure
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• acide [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazine-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique
• acido [2S-[2α,5α,6β(S*)]]-6-[[[[(4-etil-2,3-dioxopiperazin-1-il)carbonil]amino]fenilacetil]amino]-3,3-dimetil-7-oxo-4-tia-1-azabiciclo[3.2.0]heptano-2-carboxilico
• Piperacillin

Piperacillin Sodium Salt

CAS: 59703-84-3, 61477-96-1

Formula: C₂₃H₂₆N₅NaO₇S

Purity: >98.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 539.54

Ref: 3B-P1774

Piperacillin, 95%

CAS: 61477-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₃H₂₆N₅NaO₇S

Purity: 95%

Color and Shape: White, Powder or crystals or crystalline powder

Molecular weight: 539.54

Ref: 02-J66143

Piperacillin

CAS: 61477-96-1

Color and Shape: Neat

Ref: 61-FOR0295.00

(2S,5R,6R)-6-[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 517.5548

Ref: IN-DA00IAVJ

Piperacillin

CAS: 61477-96-1

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 517.56

Ref: 7W-GA9881

Piperacillin-d5 (N-ethyl-d5)

CAS: 61477-96-1

Formula: C₂₃H₂₂D₅N₅O₇S

Color and Shape: White To Off-White Solid

Molecular weight: 522.59

Ref: 4Z-P-7410

Piperacillin

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Color and Shape: White To Off-White Solid

Molecular weight: 517.56

Ref: 4Z-P-7421

piperacillin

CAS: 61477-96-1

piperacillin

Purity: ≥98%

Molecular weight: 517.55g/mol

Ref: 54-BUP16669

PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile

CAS: 10206-21-0, 104557-24-6, 113-98-4, 118443-89-3, 132-98-9, 13412-64-1, 1385046-35-4, 23325-78-2, 24356-60-3, 27164-46-1, 50370-12-2, 56238-63-2, 61336-70-7, 61477-96-1, 62893-20-3, 63358-49-6, 68373-14-8, 7081-44-9, 7177-48-2, 7240-38-2, 80370-57-6, 89786-04-9, 985-16-0

Color and Shape: Mixture

Ref: 04-A30000036WL

Piperacillin

Controlled Product

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Color and Shape: Neat

Molecular weight: 517.55

Ref: 86-MM0295.00

Piperacillin

Controlled Product

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Color and Shape: Neat

Molecular weight: 517.55

Ref: 04-C16218900

piperacillin

CAS: 61477-96-1

Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)

Formula: C₂₃H₂₇N₅O₇S

Purity: 98.32% - 98.51%

Color and Shape: Solid

Molecular weight: 517.55

Ref: TM-T8620

Piperacillin-d5 (phenyl-d5)

CAS: 61477-96-1

Formula: C₂₃H₂₂D₅N₅O₇S

Molecular weight: 522.59

Ref: 4Z-P-749

Piperacillin

Controlled Product

CAS: 61477-96-1

Applications Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);

Formula: C₂₃H₂₇N₅O₇S

Color and Shape: White

Molecular weight: 517.55

Ref: TR-P479950

Piperacillin-d5

Controlled Product

CAS: 61477-96-1

Formula: C₂₃₂H₅H₂₂N₅O₇S

Color and Shape: Off-White

Molecular weight: 522.59

Ref: TR-P479952

Piperacillin

CAS: 61477-96-1

Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.

Formula: C₂₃H₂₇N₅O₇S

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 517.56 g/mol

Ref: 3D-FE27060

Piperacillin-d5

CAS: 61477-96-1

Piperacillin-d5 is a stable isotopically labeled antibiotic, which is synthesized chemically to incorporate deuterium atoms. It is derived from the β-lactam group of antibiotics, sharing properties with its non-labeled counterpart, piperacillin. The incorporation of five deuterium atoms allows researchers to use it as a tracer in various pharmacokinetic and metabolic studies without altering its biological activity.

Formula: C₂₃H₂₂D₅N₅O₇S

Purity: Min. 95%

Molecular weight: 522.59 g/mol

Ref: 3D-AP184289