CAS 61478-26-0

1,1-Dimethylethyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylate

Description:

1,1-Dimethylethyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylate, with the CAS number 61478-26-0, is a chemical compound characterized by its pyrrolidine structure, which includes a carboxylate functional group and multiple hydroxyl groups. This compound is typically classified as an amino acid derivative due to the presence of the carboxylate group and is often involved in biochemical processes. Its stereochemistry, indicated by the (2S,4R) configuration, suggests specific spatial arrangements of its atoms, which can influence its biological activity and interactions. The presence of dimethyl groups contributes to its steric properties, potentially affecting solubility and reactivity. This compound may be of interest in pharmaceutical applications or as a biochemical reagent, given its functional groups that can participate in various chemical reactions. As with many organic compounds, its stability, solubility, and reactivity can be influenced by environmental conditions such as pH and temperature.

Formula: C₁₀H₁₉NO₄

InChI: InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-5-8(13)4-7(11)6-12/h7-8,12-13H,4-6H2,1-3H3/t7-,8+/m0/s1

InChI key: InChIKey=UFJNFQNQLMGUTQ-JGVFFNPUSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](CO)C[C@@H](O)C1

Synonyms:

• (-)-N-Boc-L-4-Hydroxyprolinol
• (2S,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
• 1,1-Dimethylethyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
• 1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S,4R)-
• 1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S-trans)-
• Boc-Hyp-Ol
• Boc-Trans-4-hydroxy-L-prolinol
• N-Boc-trans-4-hydroxy-<span class="text-smallcaps">L</span>-prolinol
• N-Boc-trans-4-hydroxy-L-prolinol
• tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate
• tert-butyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

N-Boc-trans-4-hydroxy-L-prolinol, 96%

CAS: 61478-26-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₉NO₄

Purity: 96%

Color and Shape: White, Crystalline powder

Molecular weight: 217.27

Ref: 02-H51050

(2S,4R)-tert-butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

CAS: 61478-26-0

Formula: C₁₀H₁₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 217.2622

Ref: IN-DA0035D7

Boc-trans-4-hydroxy-L-prolinol

CAS: 61478-26-0

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.26

Ref: 7W-GM4480

(2S,4R)-4-Hydroxy-2-(hydroxymethyl)pyrrolidine, N-BOC protected

CAS: 61478-26-0

(2S,4R)-4-Hydroxy-2-(hydroxymethyl)pyrrolidine, N-BOC protected

Purity: 98%

Color and Shape: White Powder

Molecular weight: 217.26g/mol

Ref: 54-OR51749

(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(hydroxymethyl)pyrrolidine

CAS: 61478-26-0

Formula: C₁₀H₁₉NO₄

Purity: >96.0%(GC)

Color and Shape: White to Yellow to Orange powder to lump

Molecular weight: 217.27

Ref: 3B-B3662

Boc-trans-4-hydroxy-L-prolinol

CAS: 61478-26-0

Formula: C₁₀H₁₉NO₄

Purity: 98%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 217.265

Ref: 10-F236730

(2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester

Controlled Product

CAS: 61478-26-0

Applications A useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents.
References Abraham, S. et al.: Bioorg. Med. Chem. Lett., 21, 5296 (2011); Huang, X. et al.: Bioorg. Med. Chem. Lett., 19, 4130 (2009); Peterson, M. & Vince, R.: J. Med. Chem., 34, 2787 (1991)

Formula: C₁₀H₁₉NO₄

Color and Shape: Neat

Molecular weight: 217.26

Ref: TR-H942835

(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(hydroxymethyl)pyrrolidine

CAS: 61478-26-0

(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(hydroxymethyl)pyrrolidine is a natural compound that has been isolated from Streptomyces sp. and found to have cytotoxic activity against human tumor cell lines. It has been shown to inhibit the growth of tumor cells in mice with induced tumors. (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(hydroxymethyl)pyrrolidine is structurally similar to pyrrolidone and has been shown to have anti-inflammatory properties as well.

Formula: C₁₀H₁₉NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 217.26 g/mol

Ref: 3D-FB60184