CAS 63-92-3
:Phenoxybenzamine hydrochloride
Description:
Phenoxybenzamine hydrochloride is a non-selective alpha-adrenergic antagonist primarily used in the treatment of conditions such as pheochromocytoma, a type of tumor that can cause excessive catecholamine release. It is characterized by its ability to irreversibly bind to alpha-adrenergic receptors, leading to prolonged vasodilation and decreased blood pressure. The compound is typically administered orally and is known for its relatively long duration of action due to its irreversible binding mechanism. Phenoxybenzamine hydrochloride is a white to off-white crystalline powder, soluble in water and alcohol, and has a pH range that is generally neutral. Its pharmacological effects can include side effects such as orthostatic hypotension, tachycardia, and nasal congestion. Due to its mechanism of action, it is important to monitor patients closely for cardiovascular responses. As with any medication, it should be used under the guidance of a healthcare professional, considering potential interactions and contraindications.
Formula:C18H22ClNO·ClH
InChI:InChI=1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H
InChI key:InChIKey=VBCPVIWPDJVHAN-UHFFFAOYSA-N
SMILES:C(N(C(COC1=CC=CC=C1)C)CCCl)C2=CC=CC=C2.Cl
Synonyms:- 2-(N-benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride
- Bensylyt Nen
- Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
- Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1)
- Benzyl(2-Chloroethyl)(1-Methyl-2-Phenoxyethyl)Amine Hydrochloride
- Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
- Dibenzylin
- Dibenzyline chloride
- Dibenzyline hydrochloride
- Dibenzyran
- Fenoxybenzamin
- N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine hydrochloride
- N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride
- N-2-Phenoxyisopropyl-N-benzyl-β-chloroethylamine hydrochloride
- N-2-phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride
- N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium
- N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium chloride
- N-phenoxyisopropyl-N-benzyl-beta-chloroethylamine hydrochloride
- NSC 37448
- Phenoxybenzamide Hydrochloride
- Phenoxybenzamide, HCl
- Phenoxybenzamine HCL
- See more synonyms
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Found 15 products.
Phenoxybenzamine Hydrochloride
CAS:Formula:C18H22ClNO·HClPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:340.29Phenoxybenzamine hydrochloride
CAS:<p>Selective alpha adrenergic blocking agent. Irreversible calmodulin inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or </p>Formula:C18H23Cl2NOColor and Shape:White to off-white, PowderMolecular weight:340.29Phenoxybenzamine hydrochloride
CAS:Phenoxybenzamine hydrochlorideFormula:C18H22CINOHClPurity:97.0%Color and Shape:WhiteMolecular weight:443.05129Phenoxybenzamine Hydrochloride
CAS:Aromatic drugs of amino-alcohols, other than those contg > one kind of oxygen function, their ethers and esters; salts thereof, nesoiFormula:C18H22ClNO·HCIColor and Shape:White Off-White PowderMolecular weight:340.29 g/molPhenoxybenzamine hydrochloride
CAS:<p>Phenoxybenzamine hydrochloride: non-selective, irreversible alpha-blocker; antihypertensive, vasodilator, may cause tachycardia, potential carcinogen.</p>Formula:C18H23Cl2NOPurity:98.04% - >99.99%Color and Shape:Antihypertensive DrugMolecular weight:340.3Phenoxybenzamine hydrochloride
CAS:Phenoxybenzamine hydrochloridePurity:≥98%Molecular weight:340.3g/molPhenoxybenzamine hydrochloride
CAS:<p>Phenoxybenzamine hydrochloride is a drug with pharmacological properties, which is used in the treatment of carcinoid syndrome. It is a combination therapy group that can be used to treat patients with neurological disorders. Phenoxybenzamine inhibits the activity of the 5-HT2 receptors and has been shown to reduce neuronal death. In addition, it has been shown to increase chemiluminescence in cells infected with HIV. Phenoxybenzamine also has effects on cardiac function and can be used to treat congestive heart failure as well as high levels of natriuretic peptides in maternal blood during pregnancy. It has also been shown to be effective against infectious diseases, such as tuberculosis and malaria.</p>Formula:C18H23Cl2NOPurity:Min. 90 Area-%Color and Shape:PowderMolecular weight:340.29 g/molPhenoxybenzamine.HCl
CAS:<p>M02323 - Phenoxybenzamine.HCl</p>Formula:C18H23Cl2NOPurity:98%+(HPLC);RGColor and Shape:SolidMolecular weight:340.29Phenoxybenzamine Hydrochloride
CAS:Controlled Product<p>Applications An irreversible α-antagonist. Used in the treatment of hypertension, it has a relatively slow onset and prolonged effect when compared to alternative α-blockers.<br>References Glass, B., et al.: J. Pharm. Pharm. Sci., 9, 398 (2006), Huang, R., et al.: Chem. Res. Toxicol., 21, 659 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C18H22ClNO·ClHColor and Shape:NeatMolecular weight:340.29
