Phenoxybenzamine hydrochloride

CAS: 63-92-3

Ref. TM-T1158

Product Information

• Name: Phenoxybenzamine hydrochloride
• Synonyms: NCI-c01661, NSC 37448, Phenoxybenzamine HCl, 2-(N-benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride, Bensylyt Nen, Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride, Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1), Benzyl(2-Chloroethyl)(1-Methyl-2-Phenoxyethyl)Amine Hydrochloride, Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride, Dibenzylin, Dibenzyline chloride, Dibenzyline hydrochloride, Dibenzyran, Fenoxybenzamin, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine hydrochloride, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride, N-2-Phenoxyisopropyl-N-benzyl-β-chloroethylamine hydrochloride, N-2-phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride, N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium, N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium chloride, N-phenoxyisopropyl-N-benzyl-beta-chloroethylamine hydrochloride, NSC 37448, Phenoxybenzamide Hydrochloride, Phenoxybenzamide, HCl, Phenoxybenzamine HCL, Phenoxybenzamine chloride
• CAS: 63-92-3

Description

Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.

• Brand: Targetmol

Chemical properties

• Molecular weight: 340.3
• Formula: C₁₈H₂₃Cl₂NO
• Purity: 100%
• Color/Form: Antihypertensive Drug