CAS 63659-19-8

Betaxolol hydrochloride

Description:

Betaxolol hydrochloride is a selective beta-1 adrenergic antagonist primarily used in the treatment of hypertension and glaucoma. It is characterized by its ability to lower heart rate and reduce cardiac output, making it effective in managing high blood pressure. As a hydrochloride salt, it is soluble in water, which facilitates its formulation in various pharmaceutical preparations. Betaxolol has a relatively long half-life, allowing for once-daily dosing in clinical settings. The compound exhibits minimal effects on beta-2 adrenergic receptors, which helps to reduce potential side effects such as bronchoconstriction, making it a safer option for patients with respiratory conditions. In ophthalmology, it is utilized in eye drops to decrease intraocular pressure in patients with open-angle glaucoma. The chemical structure of betaxolol includes a phenoxypropanolamine moiety, contributing to its pharmacological properties. Overall, betaxolol hydrochloride is recognized for its efficacy, selectivity, and safety profile in cardiovascular and ocular therapies.

Formula: C₁₈H₂₉NO₃·ClH

InChI: InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H

InChI key: InChIKey=CHDPSNLJFOQTRK-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=CC=C(CCOCC2CC2)C=C1.Cl

Synonyms:

• 1-{4-[2-(Cyclopropylmethoxy)Ethyl]Phenoxy}-3-(Propan-2-Ylamino)Propan-2-Ol Hydrochloride (1:1)
• 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride
• 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1)
• Betapress
• Betaxolol HCL
• Betaxolol Hydrochloride
• Betoptic
• Betoptima
• Kerlone
• Lusopress
• Optipress
• Sl 75212

Betaxolol Hydrochloride

CAS: 63659-18-7, 63659-19-8

Formula: C₁₈H₂₉NO₃·HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 343.89

Ref: 3B-B4474

Betaxolol Hydrochloride

CAS: 63659-19-8

Color and Shape: Neat

Ref: 61-FOR0436.00

BETAXOLOL FOR PEAK IDENTIFICATION CRS

CAS: 63659-19-8

BETAXOLOL FOR PEAK IDENTIFICATION CRS

Formula: C₈H₁₈ClNO₂

Molecular weight: 195.687

Ref: 41-Y0001360

Betaxolol hydrochloride

CAS: 63659-19-8

Betaxolol hydrochloride

Formula: C₁₈H₂₉NO₃ / C₁₈H₂₉NO₃HCl

Purity: 89.2% / 99.8%

Color and Shape: Off-White

Molecular weight: 307.21474

Ref: 47-686

BETAXOLOL HYDROCHLORIDE CRS

CAS: 63659-19-8

BETAXOLOL HYDROCHLORIDE CRS

Formula: C₈H₁₈ClNO₂

Color and Shape: Added Modified

Molecular weight: 195.687

Ref: 41-B1103000

Betaxolol Hydrochloride

CAS: 63659-19-8

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₈H₂₉NO₃·ClH

Color and Shape: White Off-White Powder

Molecular weight: 343.19142

Ref: 45-1069903

Betaxolol hydrochloride

CAS: 63659-19-8

Formula: C₁₈H₃₀ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 343.8887

Ref: IN-DA00H8YP

Betaxolol hydrochloride

CAS: 63659-19-8

Betaxolol HCl (SL 75212) is a cardioselective beta-blocker for hypertension without reported liver injury.

Formula: C₁₈H₃₀ClNO₃

Purity: 99.48% - 99.56%

Color and Shape: Solid

Molecular weight: 343.89

Ref: TM-T0226

Betaxolol hydrochloride

CAS: 63659-19-8

Formula: C₁₈H₂₉NO₃·HCl

Purity: (Titration) ≥ 98.5% (dried basis)

Color and Shape: White powder

Molecular weight: 343.89

Ref: 7W-GP0555

Betaxolol Hydrochloride

Controlled Product

CAS: 63659-19-8

Formula: C₁₈H₂₉NO₃·ClH

Color and Shape: Neat

Molecular weight: 343.89

Ref: 86-MM0436.00

Betaxolol hydrochloride

Controlled Product

CAS: 63659-19-8

Formula: C₁₈H₂₉NO₃·ClH

Color and Shape: Neat

Molecular weight: 343.89

Ref: 04-C10575500

Betaxolol Hydrochloride

CAS: 63659-19-8

Formula: C₁₈H₂₉NO₃HCl

Molecular weight: 307.43 : 36.5

Ref: ST-EA-CP-B33006

Betaxolol Hydrochloride

Controlled Product

CAS: 63659-19-8

Applications Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.
References Bickel, M., et al.: J. Pharm. Pharmacol., 32, 669 (1980), Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980), Pathe, M., et al.: Therapie, 37, 75 (1982),

Formula: C₁₈H₂₉NO₃·ClH

Color and Shape: Off-White

Molecular weight: 343.89

Ref: TR-B327980

Betaxolol HCl - Bio-X ™

Controlled Product

CAS: 63659-19-8

Betaxolol is a beta-1 adrenergic antagonist that is used for the treatment of hypertension and elevated intraocular pressure. As a result of blocking beta-1 adrenergic receptors, heart rate, blood pressure and cardiac output is reduced.

Formula: C₁₈H₂₉NO₃·HCl

Purity: (%) Min. 98%

Color and Shape: Powder

Molecular weight: 343.89 g/mol

Ref: 3D-BB164245

Betaxolol hydrochloride

Controlled Product

CAS: 63659-19-8

Beta-adrenoceptor antagonist

Formula: C₁₈H₂₉NO₃•HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 343.89 g/mol

Ref: 3D-FB18574