CAS 63659-19-8: Betaxolol hydrochloride
Description:Betaxolol hydrochloride is a selective beta-1 adrenergic antagonist primarily used in the treatment of hypertension and glaucoma. It is characterized by its ability to lower heart rate and reduce cardiac output, making it effective in managing high blood pressure. As a hydrochloride salt, it is soluble in water, which facilitates its formulation in various pharmaceutical preparations. Betaxolol has a relatively long half-life, allowing for once-daily dosing in clinical settings. The compound exhibits minimal effects on beta-2 adrenergic receptors, which helps to reduce potential side effects such as bronchoconstriction, making it a safer option for patients with respiratory conditions. In ophthalmology, it is utilized in eye drops to decrease intraocular pressure in patients with open-angle glaucoma. The chemical structure of betaxolol includes a phenoxypropanolamine moiety, contributing to its pharmacological properties. Overall, betaxolol hydrochloride is recognized for its efficacy, selectivity, and safety profile in cardiovascular and ocular therapies.
Formula:C18H29NO3·ClH
InChI:InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChI key:InChIKey=CHDPSNLJFOQTRK-UHFFFAOYSA-N
SMILES:Cl.OC(COC1=CC=C(C=C1)CCOCC2CC2)CNC(C)C
- Synonyms:
- 1-{4-[2-(Cyclopropylmethoxy)Ethyl]Phenoxy}-3-(Propan-2-Ylamino)Propan-2-Ol Hydrochloride (1:1)
- 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride
- 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1)
- Betapress
- Betaxolol HCL
- Betaxolol Hydrochloride
- Betoptic
- Betoptima
- Kerlone
- Lusopress
- See more synonyms
- Optipress
- Sl 75212
- Sld 212
