CAS 63968-75-2
:4-chloro-N-(2-methyl-1H-indol-1-yl)-3-sulfamoylbenzamide
Description:
4-Chloro-N-(2-methyl-1H-indol-1-yl)-3-sulfamoylbenzamide, with the CAS number 63968-75-2, is a chemical compound characterized by its complex structure, which includes a chloro group, an indole moiety, and a sulfonamide functional group. This compound typically exhibits properties associated with sulfonamides, such as potential antibacterial activity, due to the presence of the sulfonamide group. The indole structure contributes to its biological activity, often influencing interactions with biological targets. The chloro substituent can enhance lipophilicity, potentially affecting the compound's solubility and permeability. In terms of physical properties, it may be a solid at room temperature, with specific melting and boiling points dependent on its molecular interactions. The compound's reactivity can be influenced by the functional groups present, making it a candidate for various chemical reactions, including nucleophilic substitutions and coupling reactions. Overall, this compound's unique structure suggests potential applications in medicinal chemistry and drug development, particularly in targeting specific biological pathways.
Formula:C16H14ClN3O3S
InChI:InChI=1/C16H14ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-9H,1H3,(H,19,21)(H2,18,22,23)
SMILES:Cc1cc2ccccc2n1N=C(c1ccc(c(c1)S(=O)(=O)N)Cl)O
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Found 11 products.
Indapamide Related Compound A (4-chloro-N-(2-methyl-1H-indol-1-yl)-3-sulfamoylbenzamide)
CAS:<p>Sulfonamides, nesoi</p>Formula:C16H14ClN3O3SColor and Shape:Yellow Brown PowderMolecular weight:363.04444INDAPAMIDE RELATED COMPOUND A (50 MG) (4-CHLORO-N-(2-METHYL-INDOL-1-YL)-3-SULFAMOYLBEN-ZAMIDE) (AS)
CAS:Formula:C16H14ClN3O3SPurity:98%Color and Shape:SolidMolecular weight:363.8187Indapamide EP Impurity B (Indapamide USP Related Compound A, Dehydro Indapamide)
CAS:Formula:C16H14ClN3O3SColor and Shape:White To Off-White SolidMolecular weight:363.834-Chloro-N-(2-methyl-1H-indol-1-yl)-3-sulphamoylbenzamide
CAS:Controlled ProductFormula:C16H14ClN3O3SColor and Shape:White To Light BrownMolecular weight:363.82Dehydro Indapamide
CAS:Controlled Product<p>Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B<br>Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A<br>References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),<br></p>Formula:C16H14ClN3O3SColor and Shape:White To Light BrownMolecular weight:363.82Dehydro indapamide
CAS:<p>Dehydro indapamide is a drug that belongs to the class of antihypertensive agents. It is a prodrug that is metabolized in vivo to indapamide and hydrochlorothiazide. Dehydro indapamide has been shown to be efficacious in the treatment of hypertension, and it has a pharmacokinetic profile similar to other diuretics. The clinical data for this drug are limited, but there have been no serious side effects reported with its use.</p>Formula:C16H14ClN3O3SPurity:Min. 95%Molecular weight:363.82 g/molDehydroindapamide
CAS:<p>Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.</p>Formula:C16H14ClN3O3SColor and Shape:SolidMolecular weight:363.82
