CAS 64461-82-1
:Tizanidine hydrochloride
Description:
Tizanidine hydrochloride is a centrally acting muscle relaxant primarily used to manage spasticity associated with conditions such as multiple sclerosis or spinal cord injury. It functions as an alpha-2 adrenergic agonist, which helps reduce muscle tone by inhibiting presynaptic release of excitatory neurotransmitters. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration in tablet or capsule form. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations typically occurring within a few hours after ingestion. The drug is metabolized primarily in the liver, and its elimination half-life can vary among individuals. Common side effects may include drowsiness, dry mouth, and hypotension, necessitating caution in patients who operate heavy machinery or drive. Due to its sedative properties, it is important to monitor for potential interactions with other central nervous system depressants. Overall, Tizanidine hydrochloride is an effective therapeutic option for alleviating muscle spasticity, but it requires careful dosing and monitoring to minimize adverse effects.
Formula:C9H9Cl2N5S
InChI:InChI=1/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
InChI key:InChIKey=ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
SMILES:N(C=1C=2C(C=CC1Cl)=NSN2)C=3NCCN3.Cl
Synonyms:- 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)
- 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
- 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole hydrochloride
- 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride (1:1)
- Ab 021
- An 021
- Ds 103-282
- Sirdalud
- Ternelin
- Tizan
- Tizanidine Hydrochloride
- Tizpa
- Zanaflex
- TizanidineHydrochloride(Patent)
- 5-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2,1,3-BENZOTHIADIAZOLE-4-AMINE HYDROCHLORIDE
- 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazolehydrochloride
- Zanpeak
- Gibonz
- 5-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2,1,3-BENZOTHIADIAZOL-4-AMINE HYDROCHLORIDE
- Enchinin
- 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine, Hydrochloride, AB-021, DS-103-282, Sirdalud, Ternelin, Zanaflex
- 1,3-benzothiadiazol-4-amine,5-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-mono
- 5-Chloro-4-[(4,5-dihydro-1H-imidazol-2-yl)amino]-2,1,3-benzothiadiazole Hydrochloride
- Astonelin
- See more synonyms
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Found 19 products.
Tizanidine Hydrochloride
CAS:Formula:C9H8ClN5S·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:290.17TIZANIDINE HYDROCHLORIDE CRS
CAS:<p>TIZANIDINE HYDROCHLORIDE CRS</p>Formula:C9H9Cl2N5SColor and Shape:PowderMolecular weight:290.1723Tizanidine Hydrochloride
CAS:<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Formula:C9H8ClN5S·HClColor and Shape:White Pale Yellow Crystalline PowderMolecular weight:253.018892-[2-({[5-(diethylamino)pentan-2-yl]amino}methyl)-1-azabicyclo[2.2.2]oct-3-yl]ethanol
CAS:Formula:C9H9Cl2N5SPurity:98%Color and Shape:SolidMolecular weight:290.1723Tizanidine hydrochloride
CAS:<p>Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.</p>Formula:C9H9Cl2N5SPurity:99.96%Color and Shape:Solid WhiteMolecular weight:290.175-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)Benzo[C][1,2,5]Thiadiazol-4-Amine Hydrochloride
CAS:<p>5-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)Benzo[C][1,2,5]Thiadiazol-4-Amine Hydrochloride</p>Purity:98%Molecular weight:290.17g/molGB 31660.6-2019 α2-Agonists Mixture 169 100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:MixtureTizanidine hydrochloride 100 µg/mL in Acetonitrile
CAS:Formula:C9H8ClN5S·ClHColor and Shape:Single SolutionMolecular weight:290.17Tizanidine hydrochloride
CAS:Formula:C9H8ClN5S·HClPurity:≥ 98.0%Color and Shape:White to yellow or tan-orange powder or crystalsMolecular weight:290.175-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:290.1700134277344Tizanidine Hydrochloride
CAS:Controlled Product<p>Applications An α2-adrenergic agonist; centrally active myotonolytic. A muscle relaxant (skeletal).<br>References Turski, L., et al.: Brain Res., 379, 367 (1986), Ono, H., et al.: Gen. Pharmacol., 17, 137 (1986), Hoogstraten, M.C., et al.: Acta Neurol. Scand., 77, 224 (1988)<br></p>Formula:C9H8ClN5S·ClHColor and Shape:Light YellowMolecular weight:290.17Tizanidine HCl - Bio-X ™
CAS:<p>Tizanidine is an alpha-2 adrenergic agonist drug that is used in the treatment of muscle spasticity. This drug binds to alpha-2 adrenergic receptors and causes presynaptic inhibition of motor neurons. Additionally, it leads to a reduction in the release of amino acids such as glutamate and aspartate which have an excitatory effect.</p>Formula:C9H9Cl2N5SPurity:Min. 95%Color and Shape:PowderMolecular weight:290.17 g/molTizanidine hydrochloride
CAS:<p>α2 agonist; myotonolytic agent</p>Formula:C9H9Cl2N5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:290.17 g/mol















