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CAS 64461-82-1

:

Tizanidine hydrochloride

Description:
Tizanidine hydrochloride is a centrally acting muscle relaxant primarily used to manage spasticity associated with conditions such as multiple sclerosis or spinal cord injury. It functions as an alpha-2 adrenergic agonist, which helps reduce muscle tone by inhibiting presynaptic release of excitatory neurotransmitters. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration in tablet or capsule form. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations typically occurring within a few hours after ingestion. The drug is metabolized primarily in the liver, and its elimination half-life can vary among individuals. Common side effects may include drowsiness, dry mouth, and hypotension, necessitating caution in patients who operate heavy machinery or drive. Due to its sedative properties, it is important to monitor for potential interactions with other central nervous system depressants. Overall, Tizanidine hydrochloride is an effective therapeutic option for alleviating muscle spasticity, but it requires careful dosing and monitoring to minimize adverse effects.
Formula:C9H9Cl2N5S
InChI:InChI=1/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
InChI key:InChIKey=ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
SMILES:N(C=1C=2C(C=CC1Cl)=NSN2)C=3NCCN3.Cl
Synonyms:
  • 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)
  • 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
  • 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole hydrochloride
  • 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride (1:1)
  • Ab 021
  • An 021
  • Ds 103-282
  • Sirdalud
  • Ternelin
  • Tizan
  • See more synonyms
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Found 19 products.