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CAS 64987-85-5

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Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate

Description:
Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate, with the CAS number 64987-85-5, is a chemical compound commonly used in bioconjugation and protein labeling applications. It features a succinimidyl ester functional group, which is known for its ability to react with amine groups on proteins, facilitating the formation of stable amide bonds. The presence of a maleimide group allows for selective conjugation to thiol groups, making it particularly useful in creating targeted bioconjugates. This compound is typically characterized by its solid state at room temperature and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Its reactivity and specificity make it valuable in various fields, including biochemistry and molecular biology, for applications such as drug delivery, diagnostic assays, and the development of therapeutic agents. Proper handling and storage conditions are essential to maintain its stability and reactivity, as it may be sensitive to moisture and light.
Formula:C16H18N2O6
InChI:InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
InChI key:InChIKey=JJAHTWIKCUJRDK-UHFFFAOYSA-N
SMILES:C(N1C(=O)C=CC1=O)C2CCC(C(ON3C(=O)CCC3=O)=O)CC2
Synonyms:
  • (2,5-Dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate
  • 1-[(4-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione
  • 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-
  • 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexancarboxylate
  • 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate
  • 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester
  • 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester
  • Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester
  • N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
  • N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
  • See more synonyms
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