CAS 68-41-7

(+)-Cycloserine

Description:

(+)-Cycloserine, with the CAS number 68-41-7, is a cyclic amino acid that serves as an antibiotic and is primarily used in the treatment of tuberculosis. It is characterized by its unique structure, which includes a five-membered ring containing two functional groups: an amino group and a hydroxyl group. This compound exhibits a chiral center, resulting in its designation as the (+) enantiomer, which is biologically active. (+)-Cycloserine acts by inhibiting bacterial cell wall synthesis, specifically targeting the enzyme D-alanine racemase, which is crucial for the production of D-alanine, a building block of peptidoglycan in bacterial cell walls. The substance is soluble in water and exhibits moderate stability under standard conditions. However, it can be sensitive to light and moisture, necessitating proper storage conditions. Side effects may include neurological symptoms, which require monitoring during treatment. Overall, (+)-Cycloserine is an important compound in antimicrobial therapy, particularly for drug-resistant strains of Mycobacterium tuberculosis.

Formula: C₃H₆N₂O₂

InChI: InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

InChI key: InChIKey=DYDCUQKUCUHJBH-UWTATZPHSA-N

SMILES: N[C@H]1C(=O)NOC1

Synonyms:

• (4R)-3-Oxoisoxazolidin-4-Aminium
• (4R)-4-Amino-1,2-Oxazolidin-3-One
• (4R)-4-Amino-3-isoxazolidinone
• (R)-(+)-Cycloserine
• (R)-4-Amino-3-Isoxazolidinone
• (R)-4-Amino-3-Isoxazolidone
• (R)-4-Amino-3-isooxazolidinone
• (R)-4-Amino-Isoxazolidin-3-One
• (R)-4-Aminoisoxazolidin-3-one
• 3-Isoxazolidinone, 4-amino-, (+)-
• 3-Isoxazolidinone, 4-amino-, (4R)-
• 3-Isoxazolidinone, 4-amino-, (R)-
• <span class="text-smallcaps">D</span>-4-Amino-3-isoxazolidinone
• <span class="text-smallcaps">D</span>-4-Amino-3-isoxazolidone
• <span class="text-smallcaps">D</span>-Cycloserine
• Cicloserina
• Closerin
• Closina
• Cyclo-<span class="text-smallcaps">D</span>-serine
• Cyclo-D-serine
• Cyclorin
• Cycloserin
• Cycloserine
• D-4-Amino-3-Isoxazolidinone
• D-4-Amino-3-isoxazolidone
• D-Cs
• D-Cycloserine, Streptomyces Orchidaceus
• D-Cyloserine
• Farmiserina
• Micoserina
• Miroseryn
• Novoserin
• Nsc 154851
• Nsc 76029
• Orientomycin
• Oxamycin
• Pa 94
• Seromycin
• Tisomycin
• Wasserina

D-(+)-Cycloserine

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 102.09

Ref: 3B-C1189

D-Cycloserine, 98+%

CAS: 68-41-7

D-cycloserine, 68-41-7, is an analog of the amino acid D-alanine which exhibits broad-spectrum antibiotic properties. Learn more at Thermo Fisher Scientific.

Formula: C₃H₆N₂O₂

Purity: 98+%

Color and Shape: Powder or crystals, White to pale cream or pale yellow

Molecular weight: 102.09

Ref: 02-A18000

Cycloserine

CAS: 68-41-7

Color and Shape: Neat

Ref: 61-FOR3028.00

D-Cycloserine

CAS: 68-41-7

Originally, D-cycloserine has been used as an antibiotic in the treatment of tuberculosis. More recently, it has found application in treating anxiety disorders (see the review by S.G.Hofmann et al.). Acting as a partial agonist of the NMDA receptor, the compound reduces neuropathic pain.

Formula: C₃H₆N₂O₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 102.09

Ref: 01-4030155

CYCLOSERINE RS

CAS: 68-41-7

CYCLOSERINE RS

Ref: 41-ICRS55432

Cycloserine

CAS: 68-41-7

Antibiotics nesoi

Formula: C₃H₆N₂O₂

Color and Shape: White Off-White Powder

Molecular weight: 102.09

Ref: 45-1158005

(4R)-4-amino-1,2-oxazolidin-3-one

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 102.0919

Ref: IN-DA00IBRZ

D-Cycloserine

CAS: 68-41-7

D-Cycloserine (RO-1-9213) is an antibiotic for drug-resistant TB, used with other TB drugs.

Formula: C₃H₆N₂O₂

Purity: 98.77% - 99.01%

Color and Shape: Crystals Solid

Molecular weight: 102.09

Ref: TM-T1589

D-Cycloserine

CAS: 68-41-7

D-Cycloserine

Purity: ≥98%

Molecular weight: 102.09g/mol

Ref: 54-BUP17420

D-Cycloserine

CAS: 68-41-7

D-Cycloserine

Formula: C₃H₆N₂O₂

Purity: Assay: 982.8ug/mg (Typical Value in Batch COA)

Color and Shape: off white crystalline powder

Molecular weight: 102.09193g/mol

Ref: 54-BIC0119

D-Cycloserine

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Molecular weight: 102.09

Ref: 4Z-C-11317

D-Cycloserine

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Purity: ≥ 900μg/mg

Color and Shape: White to off-white powder

Molecular weight: 102.09

Ref: 7W-GA9717

Cycloserine

Controlled Product

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Color and Shape: Neat

Molecular weight: 102.09

Ref: 04-C11836200

Cycloserine

Controlled Product

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Color and Shape: Neat

Molecular weight: 102.09

Ref: 86-MM3028.00

D-Cycloserine-15N-d3

CAS: 68-41-7

Formula: C₃H₃D₃N₁₅NO₂

Molecular weight: 106.10

Ref: 4Z-C-11318

D-Cycloserine

Controlled Product

CAS: 68-41-7

Applications D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). D-Cycloserine also prevents conversion of D-Ala to L-Ala. D-Cycloserine is an bacteriostatic. D-Cycloserine is an antibiotic against Gram-negative bacteria. There is evidence that D-cycloserine can enhance neuronal changes that lead to learning.
References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005); Chem and Eng. News p. 12, Dec. 7/14 (2015)

Formula: C₃H₆N₂O₂

Color and Shape: Neat

Molecular weight: 102.09

Ref: TR-C988815

D-Cycloserine, Streptomyces orchidaceus

CAS: 68-41-7

M01471 - D-Cycloserine, Streptomyces orchidaceus

Formula: C₃H₆N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 102.093

Ref: 10-M01471

D-Cycloserine (D-CSR), 98%

CAS: 68-41-7

Formula: C₃H₆N₂O₂

Purity: min. 98%

Color and Shape: White to pale yellow, Powder, Clear, Colorless to pale yellow to Light pink

Molecular weight: 102.09

Ref: SR-41269

D-Cycloserine-15N,d3

Controlled Product

CAS: 68-41-7

Applications Isotope labelled D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). D-Cycloserine also prevents conversion of D-Ala to L-Ala. D-Cycloserine is an bacteriostatic. D-Cycloserine is an antibiotic against Gram-negative bacteria.
References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005),

Formula: C₃D₃H₃₁₅NNO₂

Color and Shape: Neat

Molecular weight: 106.104

Ref: TR-C988817

D-Cycloserine

CAS: 68-41-7

D-Cycloserine is a antibiotic and NMDA receptor partial agonist with action on bacterial cell wall synthesis and modulation of NMDA receptors and is used for treating tuberculosis and studying neuropsychiatric disorders.

Formula: C₃H₆N₂O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 102.09 g/mol

Ref: 3D-FC15208