CAS 680-31-9: Hexamethylphosphoramide
Description:Hexamethylphosphoramide (HMPA) is an organophosphorus compound characterized by its chemical formula C6H18N3OP. It is a colorless, odorless liquid that is highly polar and exhibits excellent solubility in water and many organic solvents. HMPA is known for its ability to act as a strong polar aprotic solvent, making it valuable in various chemical reactions, particularly in nucleophilic substitutions and polymer chemistry. Its structure features a phosphorus atom bonded to three methyl groups and a phosphoramidate group, contributing to its unique properties. HMPA is also recognized for its ability to stabilize reactive intermediates, such as carbocations and carbanions, due to its strong hydrogen-bonding capabilities. However, it is important to note that HMPA is considered toxic and poses health risks upon exposure, necessitating careful handling and appropriate safety measures in laboratory settings. Its applications extend to organic synthesis, where it serves as a solvent and reagent, as well as in the production of various chemical compounds.
Formula:C6H18N3OP
InChI:InChI=1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3
InChI key:InChIKey=GNOIPBMMFNIUFM-UHFFFAOYSA-N
SMILES:O=P(N(C)C)(N(C)C)N(C)C
- Synonyms:
- Eastman Inhibitor HPT
- Ent 50,882
- HPT
- Hempa
- Hexametapol
- Hexamethylorthophosphoric triamide
- Hexamethylphosphamide
- Hexamethylphosphoramde (HMPA)
- Hexamethylphosphoramide
- Hexamethylphosphoric Triamide
- See more synonyms
- Hexamethylphosphoric acid triamide
- Hexamethylphosphorotriamide
- Hexamethylphosphorsaeuretriamid
- Hexamethylphosporic triamide
- Hexamethyltriamidophosphate
- Hexametiltriamida Fosforica
- Hmpa
- Hmpt
- Hmpta
- Light Stabilizer HPT
- N,N',N''-Hexamethylphosphoramide
- N,N,N′,N′,N′′,N′′-Hexamethylphosphoric triamide
- Nsc 113131
- Nsc 7967
- Phosphoric acid hexamethyltriamide
- Phosphoric hexamethyltriamide
- Phosphoric triamide, N,N,N',N',N'',N''-hexamethyl-
- Phosphoric tris(dimethylamide)
- Phosphoryl hexamethyltriamide
- Triamide hexamethylphosphorique
- Tris(dimethylamino)phosphine oxide
- [Bis(dimethylamino)phosphoryl]dimethylamine
- Hexamethyl Phosphoramide
- Phosphoric triamide, hexamethyl-

Hexamethylphosphoramide
Ref: 10-F075260
1kg | 77.00 € | ||
25g | 14.00 € | ||
100g | 21.00 € | ||
500g | 48.00 € |

Hexamethylphosphoric Triamide
Ref: 3B-H0095
25g | 30.00 € | ||
100g | 71.00 € | ||
500g | 200.00 € |

Hexamethylphosphoramide
Ref: IN-DA0034ZW
1kg | 77.00 € | ||
25g | 25.00 € | ||
5kg | 192.00 € | ||
100g | 25.00 € | ||
10kg | 318.00 € | ||
250g | 36.00 € | ||
500g | 52.00 € |

Hexamethylphosphamide
Controlled ProductRef: 04-C14194700
5ml | 101.00 € |

Hexamethylphosphoramide
Ref: 54-OR13709
1kg | 129.00 € |

Hexamethyltriamidophosphate
Controlled ProductRef: TR-H294325
5g | 97.00 € | ||
100g | 160.00 € | ||
250g | 351.00 € |

Hexamethylphosphoramide
Controlled ProductRef: 3D-FH04180
1kg | 663.00 € | ||
2kg | 1,005.00 € | ||
5kg | 1,184.00 € |