CAS 680-31-9: Hexamethylphosphoramide

Description: Hexamethylphosphoramide (HMPA) is an organophosphorus compound characterized by its chemical formula C6H18N3OP. It is a colorless, odorless liquid that is highly polar and exhibits excellent solubility in water and many organic solvents. HMPA is known for its ability to act as a strong polar aprotic solvent, making it valuable in various chemical reactions, particularly in nucleophilic substitutions and polymer chemistry. Its structure features a phosphorus atom bonded to three methyl groups and a phosphoramidate group, contributing to its unique properties. HMPA is also recognized for its ability to stabilize reactive intermediates, such as carbocations and carbanions, due to its strong hydrogen-bonding capabilities. However, it is important to note that HMPA is considered toxic and poses health risks upon exposure, necessitating careful handling and appropriate safety measures in laboratory settings. Its applications extend to organic synthesis, where it serves as a solvent and reagent, as well as in the production of various chemical compounds.

Formula: C₆H₁₈N₃OP

InChI: InChI=1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3

InChI key: InChIKey=GNOIPBMMFNIUFM-UHFFFAOYSA-N

SMILES: O=P(N(C)C)(N(C)C)N(C)C

Synonyms:

• Eastman Inhibitor HPT
• Ent 50,882
• HPT
• Hempa
• Hexametapol
• Hexamethylorthophosphoric triamide
• Hexamethylphosphamide
• Hexamethylphosphoramde (HMPA)
• Hexamethylphosphoramide
• Hexamethylphosphoric Triamide
• Hexamethylphosphoric acid triamide
• Hexamethylphosphorotriamide
• Hexamethylphosphorsaeuretriamid
• Hexamethylphosporic triamide
• Hexamethyltriamidophosphate
• Hexametiltriamida Fosforica
• Hmpa
• Hmpt
• Hmpta
• Light Stabilizer HPT
• N,N',N''-Hexamethylphosphoramide
• N,N,N′,N′,N′′,N′′-Hexamethylphosphoric triamide
• Nsc 113131
• Nsc 7967
• Phosphoric acid hexamethyltriamide
• Phosphoric hexamethyltriamide
• Phosphoric triamide, N,N,N',N',N'',N''-hexamethyl-
• Phosphoric tris(dimethylamide)
• Phosphoryl hexamethyltriamide
• Triamide hexamethylphosphorique
• Tris(dimethylamino)phosphine oxide
• [Bis(dimethylamino)phosphoryl]dimethylamine
• Hexamethyl Phosphoramide
• Phosphoric triamide, hexamethyl-
• hexamethyl
• AURORA KA-1674
• ent50,882
• PHOSPHORIC ACID TRIS(DIMETHYLAMIDE)
• eastmaninhibitorhpt
• ent50882
• examethyltriamidophosphate

Hexamethylphosphoramide

CAS: 680-31-9

• Purity: 98.0%
• Color and Shape: Liquid
• Molecular weight: 179.20399475097656

Hexamethylphosphoric Triamide

CAS: 680-31-9

• Formula: C₆H₁₈N₃OP
• Purity: >98.0%(GC)(T)
• Color and Shape: Colorless to Light yellow to Light orange clear liquid
• Molecular weight: 179.20

Hexamethylphosphamide

CAS: 680-31-9

• Formula: C₆H₁₈N₃OP
• Color and Shape: Neat
• Molecular weight: 179.20

Hexamethylphosphoramide

CAS: 680-31-9

• Formula: C₆H₁₈N₃OP
• Purity: 97% (nmr) (Typical Value in Batch COA)
• Color and Shape: colourless liquid
• Molecular weight: 179.20g/mol

Hexamethyltriamidophosphate

CAS: 680-31-9

Stability Very Hygroscopic Applications Hexamethyltriamidophosphate is a known carcinogen, metabolized by CYP450 2A. Also a …

• Formula: C₆H₁₈N₃OP
• Color and Shape: Neat
• Molecular weight: 179.20

Hexamethylphosphoramide

CAS: 680-31-9

Hexamethylphosphoramide (HMP) is a glycol ether that is used as a solvent in the manufacture …

• Formula: C₆H₁₈N₃OP
• Purity: Min. 98%
• Color and Shape: Clear Colourless To Pale Yellow Liquid
• Molecular weight: 179.2 g/mol

Hexamethylphosphoramide

CAS: 680-31-9

• Formula: C₆H₁₈N₃OP
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 179.2004