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CAS 68786-66-3

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Triclabendazole

Description:
Triclabendazole is a benzimidazole derivative primarily used as an anthelmintic agent, particularly effective against liver flukes in livestock and humans. Its chemical formula is C14H9Cl3N3O4S, and it features a complex structure that includes a sulfonamide group and multiple chlorine atoms. Triclabendazole exhibits a broad spectrum of activity against various trematodes, making it a valuable compound in veterinary and human medicine. The substance is typically administered orally and is known for its relatively low toxicity in mammals, although care must be taken regarding its environmental impact and potential resistance development in target parasites. The compound is poorly soluble in water but shows better solubility in organic solvents, which influences its formulation and delivery methods. Triclabendazole's mechanism of action involves disrupting the energy metabolism of the parasites, leading to their eventual death. Its efficacy and safety profile have made it a critical tool in managing parasitic infections, particularly in regions where liver fluke diseases are endemic.
Formula:C14H9Cl3N2OS
InChI:InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
InChI key:InChIKey=NQPDXQQQCQDHHW-UHFFFAOYSA-N
SMILES:O(C=1C=C2C(N=C(SC)N2)=CC1Cl)C3=C(Cl)C(Cl)=CC=C3
Synonyms:
  • 1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-
  • 1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-
  • 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthiobenzimidazole
  • 5-Chloro-6-(2′,3′-dichlorophenoxy)-2-(methylthio)benzimidazole
  • 6-Chloro-5-(2,3-Dichlorophenoxy)-2-Methylthio-Benzimidazole
  • 6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
  • 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-benzimidazole
  • 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole
  • Cga 89317
  • Egaten
  • See more synonyms
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