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CAS 69-74-9

:

Cytarabine hydrochloride

Description:
Cytarabine hydrochloride, with the CAS number 69-74-9, is a synthetic nucleoside analog of cytidine, primarily used as an antineoplastic agent in the treatment of certain types of leukemia, particularly acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). It is characterized by its ability to inhibit DNA synthesis, thereby interfering with the proliferation of rapidly dividing cancer cells. The compound is typically administered via intravenous or subcutaneous routes due to its poor oral bioavailability. Cytarabine hydrochloride is a white to off-white crystalline powder that is soluble in water, making it suitable for injection formulations. Its mechanism of action involves incorporation into DNA, leading to chain termination during replication. The drug is known to have side effects, including myelosuppression, which can result in increased susceptibility to infections and bleeding. Additionally, it may cause gastrointestinal disturbances and neurological effects. Overall, Cytarabine hydrochloride is a critical component in the chemotherapy regimens for hematological malignancies, demonstrating significant efficacy in clinical settings.
Formula:C9H13N3O5·ClH
InChI:InChI=1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1
InChI key:InChIKey=KCURWTAZOZXKSJ-JBMRGDGGSA-N
SMILES:O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2.Cl
Synonyms:
  • 1-beta-D-arabinofuranosylcytosine hydrochloride
  • 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosylcytosine hydrochloride
  • 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosylcytosine monohydrochloride
  • 1-β-D-Arabinofuranosylcytosine hydrochloride
  • 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, hydrochloride (1:1)
  • 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, monohydrochloride
  • 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-Pyrimidin-2-One Hydrochloride
  • 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one hydrochloride (1:1)
  • 4-amino-1-pentofuranosylpyrimidin-2(1H)-one hydrochloride
  • Arabinofuranosylcytosine hydrochloride
  • See more synonyms
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Found 10 products.
  • 2(1H)-Pyrimidinone, 4-amino-1-b-D-arabinofuranosyl-,monohydrochloride
    Indagoo
    + Info

    2(1H)-Pyrimidinone, 4-amino-1-b-D-arabinofuranosyl-,monohydrochloride

    CAS:
    Formula:C9H14ClN3O5
    Purity:97%
    Color and Shape:Solid
    Molecular weight:279.6776

    Ref: IN-DA00IBW1

    1g
    25.00€
    5g
    34.00€
    10g
    46.00€
    25g
    67.00€
    100g
    182.00€
    250mg
    27.00€
  • 1-(b-D-Arabinofuranosyl)cytosine hydrochloride
    Glentham
    + Info

    1-(b-D-Arabinofuranosyl)cytosine hydrochloride

    CAS:
    Formula:C9H13N3O5HCl
    Molecular weight:279.68

    Ref: 7W-GN9186

    ne
    To inquire
  • 1-β-D-Arabinofuranosylcytosine Hydrochloride
    Apollo Scientific
    + Info

    1-β-D-Arabinofuranosylcytosine Hydrochloride

    CAS:
    <p>1-β-D-Arabinofuranosylcytosine Hydrochloride</p>
    Purity:98%
    Molecular weight:279.68g/mol

    Ref: 54-OR1009381

    1g
    32.00€
    5g
    30.00€
    25g
    59.00€
    100g
    211.00€
    500g
    959.00€
  • Cytarabine hydrochloride
    Apollo Scientific
    + Info

    Cytarabine hydrochloride

    CAS:
    <p>Cytarabine hydrochloride</p>
    Purity:≥98%
    Molecular weight:279.68g/mol

    Ref: 54-BUP14886

    50mg
    53.00€
    100mg
    76.00€
    200mg
    104.00€
    500mg
    171.00€
  • Cytarabine
    TCI
    + Info

    Cytarabine

    CAS:
    Formula:C9H13N3O5
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:243.22

    Ref: 3B-C2035

    1g
    39.00€
    5g
    114.00€
  • Cytarabine Hydrochloride
    TCI
    + Info

    Cytarabine Hydrochloride

    CAS:
    Formula:C9H13N3O5·HCl
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:279.68

    Ref: 3B-C3838

    1g
    48.00€
    5g
    118.00€
  • Cytarabine hydrochloride - Bio-X ™
    Biosynth
    + Info

    Cytarabine hydrochloride - Bio-X ™

    CAS:
    <p>Cytarabine is a pyrimidine nucleoside analogue that is used to treat leukaemia especially, non-lymphocytic leukaemia. This drug also has anti-viral and immunosuppressant properties. Cytarabine is cytotoxic and acts through direct DNA damage. Although its mechanism of action is not fully understood, it is said to inhibit DNA polymerase.</p>
    Formula:C9H13N3O5•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:279.68 g/mol

    Ref: 3D-BA164338

    100mg
    134.00€
  • Cytarabine hydrochloride
    Biosynth
    + Info

    Cytarabine hydrochloride

    CAS:
    <p>Anti-viral; anti-neoplastic</p>
    Formula:C9H13N3O5·HCl
    Purity:Min. 98 Area-%
    Color and Shape:White Powder
    Molecular weight:279.68 g/mol

    Ref: 3D-NA05780

    10g
    193.00€
    25g
    330.00€
    50g
    510.00€
    100g
    945.00€
    250g
    1,894.00€
  • Cytosine-b-D-arabinofuranoside hydrochloride
    Fluorochem
    + Info

    Cytosine-b-D-arabinofuranoside hydrochloride

    CAS:
    Formula:C9H14ClN3O5
    Purity:97%
    Color and Shape:Solid
    Molecular weight:279.68

    Ref: 10-F492690

    5g
    17.00€
    10g
    24.00€
    25g
    57.00€
    100g
    194.00€
    500g
    757.00€
  • Cytarabine hydrochloride
    Targetmol
    + Info

    Cytarabine hydrochloride

    CAS:
    <p>Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.</p>
    Formula:C9H14ClN3O5
    Purity:98.46%
    Color and Shape:White Powder
    Molecular weight:279.68

    Ref: TM-T1272L