CymitQuimica logo

CAS 69-74-9

:

Cytarabine hydrochloride

Description:
Cytarabine hydrochloride, with the CAS number 69-74-9, is a synthetic nucleoside analog of cytidine, primarily used as an antineoplastic agent in the treatment of certain types of leukemia, particularly acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). It is characterized by its ability to inhibit DNA synthesis, thereby interfering with the proliferation of rapidly dividing cancer cells. The compound is typically administered via intravenous or subcutaneous routes due to its poor oral bioavailability. Cytarabine hydrochloride is a white to off-white crystalline powder that is soluble in water, making it suitable for injection formulations. Its mechanism of action involves incorporation into DNA, leading to chain termination during replication. The drug is known to have side effects, including myelosuppression, which can result in increased susceptibility to infections and bleeding. Additionally, it may cause gastrointestinal disturbances and neurological effects. Overall, Cytarabine hydrochloride is a critical component in the chemotherapy regimens for hematological malignancies, demonstrating significant efficacy in clinical settings.
Formula:C9H13N3O5·ClH
InChI:InChI=1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1
InChI key:InChIKey=KCURWTAZOZXKSJ-JBMRGDGGSA-N
SMILES:O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2.Cl
Synonyms:
  • 1-beta-D-arabinofuranosylcytosine hydrochloride
  • 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosylcytosine hydrochloride
  • 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosylcytosine monohydrochloride
  • 1-β-D-Arabinofuranosylcytosine hydrochloride
  • 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, hydrochloride (1:1)
  • 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, monohydrochloride
  • 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-Pyrimidin-2-One Hydrochloride
  • 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one hydrochloride (1:1)
  • 4-amino-1-pentofuranosylpyrimidin-2(1H)-one hydrochloride
  • Arabinofuranosylcytosine hydrochloride
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.