CAS 70458-96-7: norfloxacin

Description: Norfloxacin is a synthetic fluoroquinolone antibiotic that is primarily used to treat bacterial infections, particularly those affecting the urinary tract and gastrointestinal system. It operates by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair, thereby preventing bacterial growth. Norfloxacin is characterized by its broad-spectrum activity against both Gram-negative and some Gram-positive bacteria. It is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability can be affected by the presence of divalent and trivalent metal ions, which can form insoluble complexes. The substance is generally considered to have a favorable safety profile, but it may cause side effects such as gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. Norfloxacin is also subject to resistance, which can limit its effectiveness. As with all antibiotics, it is essential to use norfloxacin judiciously to minimize the development of resistance and preserve its efficacy in treating infections.

Formula: C₁₆H₁₈FN₃O₃

InChI: InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

InChI key: InChIKey=OGJPXUAPXNRGGI-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN(C2=CC(=C(F)C=C2C1=O)N3CCNCC3)CC

Synonyms:

• 1,4-Dihydro-1-Ethyl-6-Fluoro-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid
• 1-Ethyl-6-Fluoro-4-Oxo-7-Piperazin-1-Yl-Quinoline-3-Carboxylic Acid
• 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 1-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
• 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
• 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 2-Hydroxypropanoic Acid
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
• 4803P
• Am 715
• Amicrobin
• Baccidal
• Barazan
• Barotham
• Chibroxin
• Chibroxine
• Chibroxol
• Esclebin
• Floxacin
• Floxacin 400
• Fulgram
• Gonorcin
• Lexinor
• Mk 0366
• N-Demethylpefloxacin
• N-Desmethylpefloxacin
• Neofloxacin
• Neofloxin
• Noflo
• Nofocin
• Nolicin
• Noracin
• Noraxin
• Norbid
• Norflox
• Norflox 400
• Norfloxacin Bayvit
• Norfloxacine
• Norfloxacine EG
• Norfloxacine Ratiopharm
• Norfloxacine Teva
• Norfloxacino
• Norfloxin
• Norilet
• Normax
• Norocin
• Noroxacine
• Noroxin
• Noroxine
• Norphloxacine
• Norxacin
• Renosept
• Sebercim
• Spectrama
• Urekacin
• Uriflox
• Uroflox
• Urotrobel
• Uroxacin
• Utin
• Utinor
• Zoroxin

Norfloxacin

CAS: 70458-96-7

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat …

• Formula: C₁₆H₁₈FN₃O₃
• Color and Shape: Cream to yellowish, Crystalline powder
• Molecular weight: 319.34

Norfloxacin for peak identification CRS

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Molecular weight: 319.3308

Norfloxacin CRS

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Molecular weight: 319.3308

Norfloxacin

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Purity: 99.3%
• Color and Shape: Light Yellow
• Molecular weight: 319.13322

Norfloxacin for system suitability CRS

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Molecular weight: 319.3308

Norfloxacin

CAS: 70458-96-7

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₁₆H₁₈FN₃O₃
• Color and Shape: White Pale Yellow Powder
• Molecular weight: 319.13322

Norfloxacin

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Purity: %
• Color and Shape: Solid
• Molecular weight: 319.33082319999994

Norfloxacin

CAS: 70458-96-7

Norfloxacin (MK-0366)(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.

• Formula: C₁₆H₁₈FN₃O₃
• Purity: 100% - 99.83%
• Color and Shape: White To Light-Yellow Crystalline Powder Solid
• Molecular weight: 319.33

Norfloxacin-d8

CAS: 70458-96-7

• Formula: C₁₆H₁₀FN₃O₃D₈
• Molecular weight: 327.34

Norfloxacin

CAS: 70458-96-7

• Molecular weight: 319.334g/mol

Norfloxacin

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Purity: ≥ 98.0% (dried substance)
• Color and Shape: White to pale yellow powder or crystalls
• Molecular weight: 319.33

Norfloxacin

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Color and Shape: Off-White To Pale Yellow Solid
• Molecular weight: 319.34

Norfloxacin, USP grade

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Purity: ≤ 0.5%
• Color and Shape: White to off-white or pale yellow powder
• Molecular weight: 319.33

Norfloxacin

CAS: 70458-96-7

• Purity: 99%
• Molecular weight: 319.33g/mol

Norfloxacin, 98%, Analytical standard

CAS: 70458-96-7

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₆H₁₈FN₃O₃
• Purity: 98%
• Color and Shape: White to yellow, Powder
• Molecular weight: 319.34

Norfloxacin 100 µg/mL in Acetonitrile

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Color and Shape: Single Solution
• Molecular weight: 319.33

GB/T 21312-2007 14 Quinolones 20 µg/mL in Methanol

CAS: 112398-08-0 14698-29-4 28657-80-9 389-08-2 42835-25-6 51940-44-4 70458-92-3 70458-96-774011-58-8 82419-36-1 85721-33-1 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-9 31430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-771751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

PharmaVetResiMix 3 Quinolones-v18 10 µg/mL in Methanol

CAS: 115550-35-1 119478-55-6 14698-29-4 149676-40-4 19562-30-2 28657-80-9 389-08-2 42835-25-6 51940-44-4 70458-96-774011-58-8 79660-72-3 82419-36-1 85721-33-1 91296-86-5 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Norfloxacin

CAS: 70458-96-7

• Formula: C₁₆H₁₈FN₃O₃
• Color and Shape: Neat
• Molecular weight: 319.33