CAS 705260-08-8

Vorapaxar sulfate

Description:

Vorapaxar sulfate is a synthetic compound primarily used as an antiplatelet medication. It functions as a protease-activated receptor-1 (PAR-1) antagonist, inhibiting thrombin-induced platelet activation, which is crucial in preventing thrombotic cardiovascular events. The substance is characterized by its ability to selectively block the PAR-1 receptor, thereby reducing the risk of heart attacks and strokes in patients with a history of cardiovascular issues. Vorapaxar sulfate is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Its pharmacokinetics are influenced by factors such as liver metabolism and protein binding. Common side effects may include bleeding complications, which necessitate careful patient selection and monitoring. Vorapaxar sulfate is often used in conjunction with other antiplatelet therapies, enhancing its efficacy in managing cardiovascular diseases. As with any medication, it is essential to consider contraindications and potential drug interactions when prescribing Vorapaxar sulfate.

Formula: C₂₉H₃₃FN₂O₄·H₂O₄S

InChI: InChI=1S/C29H33FN2O4.H2O4S/c1-3-35-29(34)32-23-10-11-24-20(14-23)15-26-27(17(2)36-28(26)33)25(24)12-9-22-8-7-19(16-31-22)18-5-4-6-21(30)13-18;1-5(2,3)4/h4-9,12-13,16-17,20,23-27H,3,10-11,14-15H2,1-2H3,(H,32,34);(H2,1,2,3,4)/b12-9+;/t17-,20+,23-,24-,25+,26-,27+;/m1./s1

InChI key: InChIKey=NQRYCIGCIAWEIC-CKLVGUEFSA-N

SMILES: C(=C/C1=CC=C(C=N1)C2=CC(F)=CC=C2)\[C@@H]3[C@]4([C@@](C[C@]5([C@]3(CC[C@@H](NC(OCC)=O)C5)[H])[H])(C(=O)O[C@@H]4C)[H])[H].S(=O)(=O)(O)O

Synonyms:

• Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate (1:1)
• Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate (1:1)
• Sch 530348
• Vorapaxar sulphate
• Zontivity
• Vorapaxar sulfate

Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate (1:1)

CAS: 705260-08-8

Formula: C₂₉H₃₅FN₂O₈S

Purity: 97%

Color and Shape: Solid

Molecular weight: 590.6602

Ref: IN-DA0039N9

Vorapaxar sulfate

CAS: 705260-08-8

Vorapaxar sulfate

Purity: ≥98%

Molecular weight: 590.66g/mol

Ref: 54-BUP08081

Vorapaxar Sulfate

Controlled Product

CAS: 705260-08-8

Formula: C₂₉H₃₃FN₂O₄·H₂O₄S

Color and Shape: Neat

Molecular weight: 590.66

Ref: 86-MM3735.00

Vorapaxar Sulfate

CAS: 705260-08-8

Formula: C₂₉H₃₃FN₂O₄·H₂SO₄

Molecular weight: 492.60 98.08

Ref: 4Z-V-050001

Vorapaxar sulfate

CAS: 705260-08-8

Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.

Formula: C₂₉H₃₅FN₂O₈S

Purity: 99.9% - >99.99%

Color and Shape: Solid

Molecular weight: 590.66

Ref: TM-T3098

Vorapaxar-d5

CAS: 705260-08-8

Formula: C₂₉H₂₈FN₂O₄D₅

Molecular weight: 497.63

Ref: 4Z-V-050002

Vorapaxar Sulfate

Controlled Product

CAS: 705260-08-8

Formula: C₂₉H₃₃FN₂O₄·H₂O₄S

Color and Shape: Neat

Molecular weight: 590.66

Ref: TR-V758200

Fosfomycin-sucrose Ether Disodium Salt

Controlled Product

CAS: 618385-01-6, 705260-08-8

Formula: C₁₅H₂₇Na₂O₁₅P

Color and Shape: Neat

Molecular weight: 524.319

Ref: TR-F727501

Vorapaxar-d5 Sulfate

Controlled Product

CAS: 705260-08-8

Formula: C₂₉D₅H₂₈FN₂O₄·H₂SO₄

Color and Shape: Neat

Molecular weight: 595.691

Ref: TR-V758202